Human Sera
Cayman Chemical BrexpIprazole 100mg
A mixture of ganglioside GM1 interacts with other proteins to increase calcium influx affecting various calcium-dependent processes including inducing neuronal outgrowth during differentiation acts as a receptor for cholera toxin and the heat-labile enterotoxin from E coli induces apoptosis in activated T cells found at higher levels on T cells isolated from patients with RCC levels are decreased in the substantia nigra pars compacta in postmortem brain from patients with Parkinsons disease accumulates in neurons in ganglioside GM1 gangliosidosis
Electron Microscopy Sciences Charcoal Cartridge
Absorb Incubator Contaminants This disposable, activated charcoal cartridge efficiently absorbs low energy 35S radioactive components during metabolic labeling. The containment problem exists in incubators and is caused by 35S-labeled amino acids, such as methionine and cysteine which are used to label proteins. The charcoal is supplied in a 100 mm diameter plastic petri dish with a highly porous membrane sealed to the top edge.
AdipoGen Pepstatin A methyl ester
Chemical. CAS 29169-91-3. Formula C35H65N5O9. MW 699.9. Cell permeable methyl ester derivative of Pepstatin A. Potent, non-competitive, transition-state analog inhibitor of gamma-secretase.
AdipoGen CD40L h multimeric CSG
Recombinant protein. Human CD40L aa 116-261 is fused at the N-terminus to mouse ACRP30headless aa 18-111 and a FLAG -tag. Induces B cells activation as demonstrated by dose-dependent upregulation of CD86 ED50 <1ng/ml. B cell expansion online protocol available. Source CHO cells. Produced using certified serum/medium.*. Liquid. Contains PBS. MultimericCD40L™ is a high-activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L in vivo. It provides a simple and equally potent alternative to CD40Lenhancer combinations. MultimericCD40L™ has been shown to suppress alum-induced IL-1beta release and caspase-1 activation in a dose-, CD40- and time-dependent manner, without affecting BMDM viability. It also effectively suppressed the inflammasome function triggered by NLRP3 activators.
Bioworld GemCell U.S. Origin Human Serum AB, 100 mL
GemCell™ human serum AB is collected from healthy male donors of the AB serotype at FDA-licensed facilities in the United States. This material is defibrinated from Source Plasma AB. All donor units are tested for viral markers (HIVAg, HBsAg, HIV 1 and 2) and found to be nonreactive.Specifications0.1µm sterile-filteredShips on dry ice.
Cayman Chemical CIsatracurIumbesylate 100mg
A topical corticosteroid with anti-inflammatory actions activates EGFR with an EC50 value of 23 nM
Cayman Chemical AtIpamezole 100mg
A 5-HT2 agonist stimulates increases in intracellular calcium levels in CHO-K1 cells expressing human 5-HT2A 5-HT2B and 5-HT2C (EC50s 447 0.9 and 32 nM respectively) selective for human 5-HT2A and 5-HT2C (Kis 32 and 1 nM respectively) over human 5-HT1A 5-HT1D 5-HT6 and 5-HT7 rat 5-HT1B and 5-HT3 and guinea pig 5-HT4 receptors (Kis ≥1995 nM) as well as adenosine A1 and A2 histamine H1-3 dopamine D1-5 a1- a2- and B1-adrenergic M1-5 muscarinic nicotinic kainate AMPA and - - and K-opioid receptors (IC50s 1000 nM) but does bind to B2-adrenergic receptors (IC50 251 nM) increases plasma levels of corticosterone oxytocin and prolactin in rats (ED50s 2.43 4.19 and 4.03 mg/kg respectively)
Cayman Chemical MacImorelInacetate 50mg
An inhibitor of FSP1 (IC50 313 nM) selective for FSP1 over NQO1 (IC50 100 UM) induces cell death in GPX4-/- H460 cells (EC50 69.36 nM) sensitizes various cancer cells to (1S3R)-RSL3-induced ferroptosis from 10-1000 nM sensitizes H460Cas9 cells to dihydroartemisinin- or FINO2-induced cell death
Cayman Chemical CapzImIn DImer 50mg
An ionizable cationic lipid (pKa ~6.1) LNPs containing LP-01 and encapsulating both Cas9 mRNA and modified sgRNA for Ttr induce gene editing in liver cells in mice in a dose-dependent manner resulting in reduced serum Ttr levels for at least 12 months subretinal administration of LNPs containing LP-01 and encapsulating both Cas9 mRNA and sgRNA targeting the loxP stop codon induce retinal gene editing in Ai9 mice
Cayman Chemical RopIdoxurIdIn 50mg
An analytical reference standard categorized as a piperazine intended for research and forensic applications
Cayman Chemical 2deoxy2fluoroDGlucose 100mg
An ER modulator acts as an ER antagonist in humans sheep and rabbits and an ER agonist in rats inhibits E2 binding in isolated rabbit uterus at 0.34 UM decreases E2-induced inhibition of FSH secretion in primary sheep pituitary cells in a concentration-dependent manner inhibits spermatogenesis and decreases serum LH and testosterone levels in intact or castrated rats at 0.25 and 0.5 mg/animal