Human Sera
Cayman Chemical Plumula nlumbns nfern 50mg
An internal standard for the quantification of drospirenone by GC-or LC-MS
Cayman Chemical SImvastatIn Hydroxy ACDam 50mg
A fungicide inhibits SDH (IC50 5 2 nM) inhibits mycelial growth of S sclerotiorum (EC50 0 011 Ug/ml) completely protects eggplant leaves from S sclerotiorum infection at 60 Ug/ml
Cayman Chemical SulfamIdopyrInsodIM salt 100mg
An inhibitor of ecto-5-nucleotidase (Ki 37 nM) inhibits AMP- ADP or ATP-induced cAMP accumulation in VA-13 human fibroblasts at 100 UM reduces proliferation of U138MG glioma cells as well as inhibits the invasion and migration of MHCC97H HCC cells in a migration assay increases tumor infiltration of CD3 CD8 T cells and reduces tumor growth in a K1735 murine melanoma model
Cayman Chemical CytarabIn 5-monphosphate 50mg
A positive allosteric modulator of mGluR5 potentiates glutamate- quisqualate- or 35-dihydroxyphenylglycine-induced calcium transients in CHO cells expressing human mGluR5 (EC50s 0 021 0 642 and 2 4 UM respectively) enhances quisqualate-induced phosphatidylinositol hydrolysis in rat hippocampal slices (EC50 0 42 UM) improves spatial alternation retention in the Y-maze special alternation task in rats
Cayman Chemical Nacetyl2 3dehydro2Deoxyn 50mg
An inhibitor of TG2 (IC50 7 71 UM) cytotoxic against a panel of eight RCC cell lines (mean GI50 0 905 UM) suppresses tumor growth in ACHN and Caki-1 RCC mouse xenograft models at 8 mg/kg
Cayman Chemical 3-Alylphenol 50mg
Immunogen Mouse IgG2a Host Rabbit Species Reactivity ( ) Mouse Cross Reactivity ( ) IgG2a (-) Mouse IgG1 IgG2b IgG2c IgG3 IgM IgA IgE (-) Human rat IgG Applications ELISA WB (non-reducing conditions) MW 150 kDa
Cayman Chemical 2DeoxyadenosIn5OdIphos 50mg
A STING agonist binds to STING (IC50 0 32 nM) and induces STING transcriptional activity in a reporter assay (EC50 31 62 nM) increases protein levels of NLRP3 IL-1B and IL-18 in macrophages
Cayman Chemical 5 7DICLOrothIazolo5 4dpy 100mg
A metabolite of indomethacin decreases the viability of HL-60 cells when cultured with glucose oxidase at 600 UM has been used in the synthesis of PGD2 receptor antagonists
Cayman Chemical NaBenzoylLArgInInpNAhy 100mg
An internal standard for the quantification of chlorzoxazone by GC- or LC-MS
Cayman Chemical CInamoylglycIn 50mg
A fungal metabolite inhibits Mg2 - Ca2 - and Na /K -ATPase activities in equine erythrocyte ghosts by 81 58 and 23 respectively at 200 Ug/ml cytotoxic to Sf9 and Sf21 insect cells (CC50s 4 91 and 12 12 UM respectively)
Cayman Chemical nglca pubscns Subrosn 100mg
A derivative of maytansine cytotoxic to SK-BR-3 cells (IC50 3 3 nM) selectivity cytotoxic to a variety of CD205-expressing human cancer cells (EC50s 0 1-1 32 nM) over non-CD205-expressing cells (EC50s 14 2-22 66 nM) and reduces tumor growth in various mouse xenograft and PDX cancer models when conjugated to a humanized CD205-targeting monoclonal antibody
Cayman Chemical RhosInhydrochlorIde 50mg
A potential impurity found in commercial preparations of olanzapine a degradation product formed by exposure to thermal or oxidative stress
Cayman Chemical DSthIazlylmthyl RItonavIr 50mg
An alkaloid with diverse biological activities inhibits arachidonic acid- collagen- thrombin- or PAF-induced platelet aggregation in washed isolated rabbit platelets at 100 Ug/ml cytotoxic to human KB oral HeLa cervical and DLD-1 colon cancer cells (EC50s 20 55 2 5 and 6 4 Ug/ml respectively) and induces apoptosis in A549 PC-9 and EBC-1 human lung cancer cells from 50-200 UM increases serum ALT and ALP activities and induces hepatocyte necrosis in mice at 150 or 200 mg/kg
Cayman Chemical A2764hydrochlorIde 50mg
A pyrimidine nucleoside derivative inhibits dihydroorotase (Ki 340 UM for the rat enzyme) sensitizes Don Chinese hamster lung cells to irradiation has been used in the synthesis of compounds with antiviral and anticancer activities
Cayman Chemical CnabIdIvarIn 50mg
A disulfide with antitumor and antiplatelet activities cytotoxic to a variety of cancer cells (IC50s 7-38 UM) reduces tumor growth and decreases the number of lung metastases in murine models of melanoma at 25 mg/kg prevents thrombus formation in heparinized animals in a porcine model of severe vascular damage at 25 mg/kg