Human Sera
Cayman Chemical PIperonyl ButoxIde 100mg
An insecticide synergist; inhibits CYP activity in western corn rootworm abdominal microsomes; increases the toxicity of deltamethrin to field-collected, deltamethrin-resistant strains of the bed bug C. lectularius by 5.6- to 176-fold at 50 μg/μl; increases the toxicity of cyhexatin to fourth instar larvae of susceptible strains of the cotton leafworm S. littoralis; not toxic to the freshwater invertebrates H. azteca, C. tentans, and L. variegatus (LC50s = 530, 2,740, and 3,540 μg/L, respectively) and reduces the toxicity of diazinon, chlorpyrifos, and azinphos-methyl
Cayman Chemical Flumethason 100mg
An agonist of glucocorticoid and mineralocorticoid receptors (EC50s = 0.26 and 0.494 nM, respectively, in CV-1 cells expressing human receptors); inhibits the growth of UM-UC-3, TCC-SUP, and 5637 urothelial carcinoma cell lines (100 nM); decreases TNF production ex vivo in blood cells collected by BAL from calves with experimentally-induced local lung inflammation (5 mg per animal); impairs cell cycle re-entry of cardiac cells seven days post cryo-injury to the heart and impairs cardiac regeneration in vivo in zebrafish (5 μM)
Cayman Chemical AlarelInacetate 50mg
A peptide agonist of GnRH; binds to GnRHR (Kd = 0.2 nM); decreases GnRH and GnRHR expression in the preoptic area and pMBH, respectively, of ovariectomized estradiol-treated rats at 6 ng, i.c.v., indicating an ultrashort negative feedback loop; induces desensitization in the pituitary and decreases serum estradiol levels and ovarian and uterine weight in neonatal and adult female rats; reduces tumor growth in an HEC-1-B mouse xenograft model at 20, 40, and 80 UG/mg
Cayman Chemical LOMEGUATRIB 50MG
A modified quanine base which acts as a pseudosubstrate inactivator of MGMT (IC50 = ~3 nM)
Cayman Chemical PergolIdemesylate 100mg
A potent and selective Syk inhibitor (IC50 4 nM) inhibits 92 of Syk activity while other kinases retain 70 activity at a concentration of 50 nM in a panel of 270 kinases inhibits convulxin-induced aggregation of human platelet-rich plasma (IC50 2.5 M) prevents thrombosis in a transgenic mouse model of heparin-induced thrombocytopenia induces CLL B cell apoptosis and inhibits the secretion of chemokines CCL3 CCL4 and CXCL13 inhibits CLL B cell chemotaxis and pseudoemperipolesis
Cayman Chemical Docosahexaenoyl GlycIn 100mg
Consists of docosahexaenoic acid, an ω-3 PUFA, with glycine attached at its carboxy terminus
Cayman Chemical Aunt fumatuus Nautn 50mg
A flavanone; reduces airway sensitivity, eosinophil counts and IL-4 levels in BALF, and serum IgE levels in a mouse model of ovalbumin-induced airway inflammation at 10 mg/kg; decreases immobility in the forced swim test and latency to feeding in the novelty-suppressed feeding test, indicating antidepressant-like activity in mice
Cayman Chemical DerythroLthreo Lysosphngo 50mg
A mixture of the bioactive sphingolipids D-erythro and L-threo lysosphingomyelin
Cayman Chemical 4NItrophenyl aLrhamnopyrn 50mg
A colorimetric naringinase substrate; upon hydrolysis by the α-rhamnosidase subunit of naringinase, 4-nitrophenol is released which can be quantified by colorimetric detection at 405 nm as a measure of naringinase α-rhamnosidase activity; has been used in the detection of naringinase α-rhamnosidase activity in various bacteria
Innovative Research Inc Single Donor Human Rheumatoid Arthritis Serum
Single Donor Human Rheumatoid Arthritis Serum from Innovative Research is whole blood derived. Available volumes are variable, and range from 0.5ml to 1.0ml per vial (you can select your exact samples from our inventory, if desired). A detailed patient history and clinical information is recorded at the time of draw, and multiple samples and plasma/serum matched sets from the same donor are often available.
Innovative Research Inc Pooled Human Serum Lyophilized 1gm
Pooled Human Serum Lyophilized from Innovative Research is 0.2 micron filtered, lyophilized pooled serum.
Innovative Research Inc Pooled Human AB Serum Plasma Derived Heat Inactivated 100ml
Pooled Human AB Serum Plasma Derived and Heat Inactivated from Innovative Research is collected from male donors with blood type AB. The plasma (collected via apheresis) is processed into serum at FDA-licensed facilities located in the United States. Our Pooled Human AB Serum is filtered and cell culture tested for mycoplasma, endotoxin, and sterility. The serum then undergoes a heat inactivation process to destroy complement activity. This product is suitable for use in cell culture applications.
Cayman Chemical STetrahydrofurn2ylmeth 50mg
A synthetic intermediate useful for pharmaceutical synthesis.
Cayman Chemical Desmethylen ParoxetInhydr 50mg
A major urinary metabolite of the selective serotonin reuptake inhibitor paroxetine; may be used as a control in LC/MS or GC/MS paroxetine testing applications
Cayman Chemical NortrIptylInhydrochLRIde 100mg
A tricyclic antidepressant that blocks norepinephrine and serotonin transporters (KDs = 4.4 and 18 nM, respectively) more potently than the dopamine transporter (KD = 1.1 µM)