Human Sera
Cayman Chemical 7 DIethylamInocoumarIn3ca 50mg
A glycolipid TLR4 antagonist inhibits lipid A-induced TLR4 activation in a cell-based assay (IC50 5 013 UM) reduces LPS-induced lethality in mice at 10 mg/kg decreases angiotensin II-induced aortic expansion and rupture as well as the incidence of abdominal aortic aneurysms in ApoE-/- mice at 3 mg/kg
Cayman Chemical HydrocortIson Aceponate 50mg
A flavonoid glycoside with diverse biological activities inhibits RANKL-induced osteoclastogenesis in RAW 264 7 cells at 5 UM inhibits Aurora B kinase (IC50 11 07 UM in a cell-free assay) as well as Aurora A kinase and RSK2 at 20 UM induces cell cycle arrest at the G2/M phase and apoptosis in HGC-27 cells decreases LDH release induced by DL-buthionine (SR)-sulfoximine in primary rat cortical cells (IC50 7 4 Ug/ml) reduces acetic acid-induced writhing in mice
Cayman Chemical 3 6-DIsInapoylsucrose 50mg
A very long-chain saturated fatty acid a component of D-003
Cayman Chemical DIhydrojasmonIc AcId 100mg
A fluorescent membrane potential indicator displays excitation/emission maxima of 490/516 nm respectively has been used to measure the membrane potential of live or fixed mammalian and bacterial cells by flow cytometry or fluorescence microscopy
Cayman Chemical PhenylacetylglycIn 100mg
An active metabolite of chlorpromazine increases plasma prolactin levels in male rats at 5 mg/kg reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats at 1 6 mg/kg
Cayman Chemical Tocopherol 50mg
Source Active recombinant human HGF expressed in CHO cells Amino acids 32-728 MW 79 7 kDa
Cayman Chemical GemcItabInhydrochlorIde 50mg
An ionizable cationic lipid has been used in the formation of LNPs for the delivery of mRNA in vitro and in vivo LNPs containing lipid U-101 and encapsulating mRNA encoding a fusion protein composed of IL-2 a linker and CD25 inhibit tumor growth in an MC-38 mouse xenograft model
Cayman Chemical ArachIdonyl EthnolamIde 100mg
Source Recombinant human N-terminal His-tagged HR5A1 (C247S C412S mutant) expressed in E. coli Amino acids 218-461 MW 31.01 kDa
Cayman Chemical -2-Methyl ArachIdonyl-2- 50mg
A peptide increases jejunum and ileum crypt depth and villus height without disrupting gut microbiota diversity in rats at 0.9 mg/kg four days per week decreases lapatinib-induced diarrhea severity and incidence in rats prevents lapatinib-induced loss of body weight in rats
Cayman Chemical 1Oleoyl2hydroxysnglycero 50mg
A macrocyclic depsipeptide anthelmintic inhibits locomotion in C. elegans (IC50 14 nM) an effect that can be reversed by knockout of the gene encoding SLO-1 decreases the survival of N. brasiliensis and S. ratti worms in infected rats and H. polygyrus worms in infected mice at 10 mg/kg
Cayman Chemical DIhomoLInolenoyl Ethnolam 50mg
A synthetic intermediate in the synthesis of capzimin
Cayman Chemical 4MethylNmethylhexnopheno 50mg
A TLK2 inhibitor (IC50 18 nM) selective for TLK2 over TLK1 TrkC and FLT3 at 500 nM and a panel of 468 kinases at 1 UM but it does inhibit 11 kinases by >90 in the same panel
Cayman Chemical Ionone ACD 50mg
An analytical reference standard categorized as a steroid intended for research and forensic applications
Cayman Chemical DocosatrIenoIc AcId 100mg
An inhibitor of the LFA-1/ICAM-1 interaction binds to LFA-1 and blocks the adhesion of Jurkat T cells or HuT 78 cells to ICAM-1 (IC50s 2.98 and 9 nM respectively) and inhibits secretion of various cytokines from these cells increases tear production in dogs with idiopathic keratoconjunctivitis sicca topical application inhibits LFA-1-dependent neutrophil recruitment to the eye in mouse models of contact lens-associated corneal inflammation induced by corneal abrasion and tobramycin-killed bacteria