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This gene encodes a member of the S1 or chymotrypsin family of serine peptidases This protease catalyzes the cleavage of factor B the rate-limiting step of the alternative pathway of complement activation This protein also functions as an adipokine a cell signaling protein secreted by adipocytes which regulates insulin secretion in mice Mutations in this gene underlie complement factor D deficiency which is associated with recurrent bacterial meningitis infections in human patients Alternative splicing of this gene results in multiple transcript variants At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease
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The R-PLEX Human Complement C3 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures levels of complement component C3 in human serum plasma and other biological samples This assay utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer blocker reagents and calibrator This assay allows for the quantitative measurement of complement C3 levels which can aid in the diagnosis of immunological and inflammatory conditions
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Intralipid for Interference Testing is a highly concentrated intralipid solution (20perc) used to test intralipids interference in various assays This product is for in vitro research use only and is not for use on humans For in vitro research use only
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