Guinea Pig Whole Blood
Cayman Chemical NordIhydroguaIaretIc ACD 500mg
An inhibitor of FAP (IC50 3.2 nM) selective for FAP over prolyl endopeptidase DPP-4 DPP-9 and DPP-2 (IC50s >1.8 >100 >12.5 and >100 UM respectively)
Cayman Chemical DocosahexaenoIc ACD ethyl S 1g
A PEGylated form of C16 ceramide has been used in the generation of microspheres LNPs and liposomes for the delivery of small molecules mRNA and plasmid DNA in vitro and in vivo liposomes containing C16 MPEG(2000) ceramide with a stearylated-INF7 and have been used to transfect plasmid DNA into MFLM-4 cells microspheres containing C16 MPEG(2000) ceramide and encapsulating oxaliplatin increase survival and decrease the number of small intestine colon and cecum polyps in an Apc /Minz spontaneous colorectal adenoma mouse model
Sigma Aldrich Fine Chemicals Biosciences Alsevers Solution liqids500ML
Alsevers SOLUTIONon liqids500ML
Cayman Chemical compre Faty ACD Meth 1mL
A dual inhibitor of PI3K and mTOR (IC50s 3 4 12 16 and 16 nM for PI3Ka PI3KB PI3K and PI3KY respectively) inhibits proliferation of PC3 and MCF-7 1 cells (IC50s 330 and 180 nM respectively) reduces tumor volume in PC3 and MCF-7 1 mouse xenograft models at 10 mg/kg per day
Cayman Chemical 3 3SulfInyldIpropnoIc ACD
A peptide substrate for PKC selective for PKC over PKA CK1 CK2 phosphorylase kinase and CaMKII has been used to monitor PKC activity in primary human renal artery smooth muscle cells
Cayman Chemical 4HydroxyphenylglyoxylIc ACD
A dual inhibitor of p70S6K and Akt1 (IC50s 1.1 and 4 nM respectively) selective for p70S6K and Akt1 over Aurora B kinase (IC50 170 nM) as well as a panel of 265 kinases at 1 UM inhibits PKA MSK1 MSK2 PKG1a PKG1B and PRKX reduces tumor volume in A549 and MiaPaCa-2 mouse xenograft models at doses of 20 or 30 mg/kg respectively
Cayman Chemical ProstatIc ACD Phosphatsem
A peptide antagonist of PAR4 inhibits platelet aggregation induced by AYPGKF-NH2 in washed isolated rat platelets (IC50 95-190 UM) induces relaxation of isolated rat aortic rings precontracted with phenylephrine and contraction of isolated rat gastric longitudinal muscle strips (EC50s 64 and 1 UM respectively) inhibits thrombin-induced migration of primary HCC cells at 400 UM reduces myocardial infarct size as a percentage of the area at risk ex vivo in an isolated rat heart model of ischemia-reperfusion injury
Cayman Chemical 2Hydroxy Faty ACD Methyl10mg
An adenosine A2B receptor antagonist (Ki 53.4 nM) selective for A2B over A1 and A2A receptors which have Ki values of 2200 and 24000 nM respectively selective for A2B over the A3 receptor which is inhibited only 14 at a concentration of 10 UM pre-treatment of rat trachea reduces relaxation induced by repeated dosing of the non-selective adenosine agonist NECA
Cayman Chemical DocosahexaenoIc ACD Alkyn
A long-acting ascorbic acid derivative that stimulates collagen expression and formation and is used in human cell culture included in media to enhance the survival of human embryonic stem cells or drive osteogenic differentiation in human adipose stem cells and in human mesenchymal stromal/stem cells
Cayman Chemical 8 Z 14 ZEIcosadIenoIc ACD
A paramagnetic nitroxide spin label featuring a methanethiosulfonate group for site-directed spin labeling particularly through disulfide linkages with cysteine residues on proteins
Cayman Chemical 3AmInopropylphosphonIc ACD
A chromone complex that acts as a mast cell stabilizer to prevent the release of histamine
Cayman Chemical 3AmInopropylphosphonIc ACD
A chromone complex that acts as a mast cell stabilizer to prevent the release of histamine
LAMPIRE Biological Laboratories GUINEA PIG BLOOD K2 EDTA 50ML
Guinea Pig, Whole Blood, K2 Edta, Donor, Gender Unspecified, 50 Ml
Cayman Chemical LNgchaIn Faty ACD Methyl 100mg
A diacylglycerol has been found in olive oil subjected to lipase-catalyzed glycerolysis with immobilized lipase B from C antarctica