Primary Antibody Matched Pairs
Cusabio Technology LLC HUMAN GSTO1 ELISA KIT
This kit detects GSTO1 in human serum plasma tissue homogenates and cell lysates using a sensitive sandwich ELISA method It offers a broad detection range of 31 2 pg/mL to 2000 pg/mL with a high sensitivity of 7 8 pg/mL ensuring accurate quantification of low-abundance targets The assay requires a short incubation period of 1 to 5 hours and a modest sample volume of 50-100 L per test Detection is performed at 450 nm and the kit is designed for reliable performance in both research and clinical settings Its standardized protocol supports consistent results across diverse sample types making it suitable for studies focused on oxidative stress detoxification pathways or biomarker analysis related to GSTO1 expression
Sino Biological Anti-PNMA2 Antibody, Rabbit Polyclonal 100 µL
Produced in rabbits immunized with E. coli-derived Human PNMA2 fragment, and purified by antigen affinity chromatography.
Biotium Perforin-1 (Pore Forming Protein) (Apoptosis Marker) (PRF1/2468), CF405S conjugate, 0.1mg/mL
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8 T-cells, natural killer cells and some CD4 T-cells.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of
Medchemexpress LLC S100A8-S100A9 Hetero 500ug
Recombinant human S100A8-S100A9 heterodimer supplied as a His-tagged solution and expressed in E. coli. The calcium- and zinc-bound complex is involved in inflammatory and immune responses, contributes to leukocyte function, regulates the cytoskeleton, and can activate intracellular NADPH oxidase. Provided in a research-grade formulation for biochemical and cell-based assays.
- Recombinant human heterodimer expressed in E. coli.
- Includes His tag for detection and purification.
- Contains calcium- and zinc-bound S100A8 subunit.
- Suitable for biochemical and cell-based inflammation studies.
- Supplied as a stabilized solution for easy handling.
ABclonal Technology RALBP1 Rabbit mAb
RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA, MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS, MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).
ABclonal Technology RheB Rabbit pAb
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Cayman Chemical RAD51-IN-17 25mg
A RAD51 inhibitor; inhibits DNA damage-induced RAD51 foci formation in MDA-MB-231 TNBC cells at 10 µM; enhances irradiation-induced reductions in the proliferation of MDA-MB-231 cells at 10 µM
Sino Biological Recombinant Human CD70/CD27 Ligand Protein (Site-Specific PE Conjugation, ECD, Trimer, His Tag)
A DNA sequence encoding the human CD70 (NP_001243.1) (Gln 39-Pro 193) was expressed with a N-terminal polyhistidine tag. This construct has a trimer design.The protein is site-specifically conjugated with PE (Excitation = 495-566 nm, Emission Max.= 575 nm).
ABclonal Technology MATN2 Rabbit pAb
This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Human IFNG ELISA Pair Set 15PP (Sino Biological)
Each vial contains 19 ng of recombinant Human Interferon Gamma/IFN gamma/IFNG. Reconstitute with 1 mL Dilution Buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial in Dilution Buffer, and a high standard of 1400 pg/mL is recommended.
Biotium S100A9(47-8D3), 0.2mg/mL
This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylate
Biolegend Purified anti-S100A8
Purified anti-S100A8 [A22124D]; Isotype: Mouse IgG2b, λ; Reactivity: Human; Apps: WB, IHC-P, ICC; Size: 100 μg
Biotium GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/1960), Biotin conjugate, 0.1mg/mL
This MAb recognizes a protein of 65 kDa, which is identified as glutamic acid decarboxylase 2 (GDA2). It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GAD s) that are found in the brain: GAD2 (also known as GAD65) and GAD1 (also known as GAD67). GAD1 and GAD2 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (ÃŽ³-aminobutyric acid) from L-glutamic acid. Although both GAD s are found in the brain, GAD2 localizes to synaptic vesicle membranes in nerve terminals, while GAD1 is distributed throughout the cell. A pathogenic role for GAD2 is identified in the human pancreas since it has been identified as an autoantibody and an auto-reactive T cell target in insulin-dependent diabetes.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other label
ABclonal Technology TP53RK Rabbit pAb
Enables p53 binding activity and protein serine/threonine kinase activity. Involved in protein phosphorylation. Located in cytoplasm and nucleus. Part of EKC/KEOPS complex. Implicated in Galloway-Mowat syndrome 4.
Biotium RAD51 (Prognostic and Response to Chemotherapy Marker)(RAD51/2753), Biotin conjugate, 0.1mg/mL
RAD51 is one of the key factors of DNA repair by homologous recombination and has been shown to have anti-apoptotic activity in tumor cells. RAD51 protein interacts with a variety of tumor suppressor proteins including p53, BRCA1 and BRCA2. Elevated expression of RAD51 enhances radio-resistance of human tumor cells. Overexpression of RAD51 protein in tumor cells renders them resistant against cytotoxic drugs like Cisplatin. RAD51 interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of RAD51. High-level expression of RAD51 has been observed in a variety of human malignancies. RAD51 overexpression correlates with histological grading of the tumor in invasive ductal mammary carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightnes