Apoptosis Reagents and Kits
American Research Products Inc Rat Factor related Apoptosis l
Rat Factor-related Apoptosis ligand FASL ELISA Kit from CUSABIO Detection Range 31 25 pg/mL-2000 pg/mL Sensitivity 7 8 pg/mL Sample serum plasma tissue homogenates Method Sandwich
AdipoGen WP1130
Chemical. CAS 856243-80-6. Formula C19H18BrN3O. MW 384.3. WP1130 is a second-generation tyrphostin derivative initially identified as a JAK2 signaling inhibitor through JAK2 ubiquitination that reduces STAT activation stimulated by cytokines such as IL-6 and IL-3 through the rapid down-regulation of upstream JAK kinases. WP1130 has also been identified as a partially selective cell permeable deubiquitinating enzyme/deubiquitinase DUB inhibitor that directly inhibits DUB activity of USP9x, USP5, USP14, USP24, UCH37, UCHL1 and UCHL5, leading to rapid accumulation of polyubiquitinated K48/K63-linked proteins into juxtanuclear aggresomes and tumor cell apoptosis, accounting for its anti-cancer properties. Through this mechanism, WP1130 has been shown to downregulate the antiapoptotic proteins Bcr/Abl and Jak2 and to upregulate the proapoptotic proteins MCL-1 and p53.
Cayman Chemical Z-VAD-AMC (acetate), Purity: ≥95%, 5 mg
A caspase-1 fluorogenic substrate; upon enzymatic cleavage, AMC is released and its fluorescence can be used to quantify enzyme activity; ex/em = 340-360/440-460 nm, respectively
Abcam Cathepsin D Inhibitor Assay¿Kit
Cathepsin D Inhibitor Assay¿Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human HSP90AB1 (Hsp90 beta) knockout A-431 cell lysate.
Human HSP90AB1 (Hsp90 beta) knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC ML-7 HCl 10mg 110448-33-4
ML-7 is an inhibitor of smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 ¿M and displays reversible, ATP-competitive inhibition of Ca2+-calmodulin-dependent and -independent smooth muscle MLCKs. ML-7 also inhibits PKA and PKC with Ki of 21 ?M and 42 ?M, respectively. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC HY-100894 1mg Medchemexpress, Biotin-VAD-FMK CAS:1135688-15-1 Purity:>98%
Medchemexpress, HY-100894 1mg Biotin-VAD-FMK CAS:1135688-15-1 Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Abcam Human PPP1CC (PP1C gamma) knockout HeLa cell lysate.
Human PPP1CC (PP1C gamma) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human STK24 knockout A-431 cell lysate.
Human STK24 knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Kinetic Apoptosis Kit (Microscopy)
Kinetic Apoptosis Kit (Microscopy)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human VCL (Vinculin) knockout HeLa cell lysate.
Human VCL (Vinculin) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement