Signal Transduction Reagents and Kits
Axxora LLC c-diGMP | 61093-23-0 | MFCD31563661 | 1 umol
c-diGMP | Purity: 98% | Mol Wt: 690.4 | 61093-23-0 | MFCD31563661 | 1 umol
Medchemexpress LLC Reticuline | 485-19-8 | 329.39 | 5 MG
Reticuline demonstrates anti-inflammatory effects by influencing the JAK2/STAT3 and NF-κB signaling pathways. It decreases the mRNA expression of TNF-α and IL-6, and reduces the phosphorylation levels of JAK2 and STAT3. Additionally, Reticuline exhibits cardiovascular effects.
- Inhibits mRNA expressions of TNF-α and IL-6.
- Reduces phosphorylation levels of JAK2 and STAT3.
- Exhibits cardiovascular effects.
- Purity: 98.89%.
- Appearance: Solid, white to yellow.
- For research use only.
Echelon Biosciences Research Labs SHUTTLE PIP KIT PI(5)P
Echelon Biosciences - Shuttle PIP Kit - P-9005 - PI(5)P This item is non returnable
Montana Molecular Green Ratiometric Cilia-Targeted cADDis cAMP Sensor Kit D0211G, 10mL, CMV
Measure real-time cAMP signaling kinetics in the primary cilia with this live cell fluorescent assay. Add cADDis to your cells and measure robust signals the next day on a fluorescence imaging system. Decreasing green fluorescence indicates ciliary cAMP increase. Constitutively expressed cytosolic red fluorescence can be used for ratiometric measurements. This assay is genetically encoded and packaged in BacMam for efficient delivery to cilia in most cell types, including many primary and iPSC-derived cells.
Apexbio Technology LLC Aurora Kinase Inhibitor III 879127-16-9 1mg
Aurora Kinase Inhibitor III (CAS 879127-16-9) is a selective small molecule inhibitor targeting Aurora A kinase It acts by binding to the ATP-binding site of Aurora A thereby suppressing its enzymatic activity with an IC50 of 42 nM The compound exhibits substantially lower inhibitory potency against epidermal growth factor receptor (EGFR) with an IC50 greater than 10 M Aurora Kinase Inhibitor III serves as a useful chemical probe for investigating Aurora A-mediated processes including mitotic regulation cell cycle progression and associated signaling pathways and supports studies exploring the role of Aurora A in oncogenesis
Selleck Chemical LLC Zolmitriptan 10mg 139264-17-8
Zolmitriptan is a novel and highly selective 5-HT(1B/1D) receptor agonist, used in the treatment of acute migraines. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Takara Bio Lenti-X GoStix Plus, 10 Minute quantitative lentiviral titer tests
Lenti-X GoStix Plus; Quantify lentivirus titer in 10 minutes; 50 Tests
Cell Biolabs Inc ViraDuctin™ Retrovirus Transduction Kit, 40 transductions
The rate at which retroviral vectors bind to and infect cells is mostly controlled by diffusion. During retrovirus infection, only a small fraction of the retroviral vectors can transduce target cells. Virion adsorption is the limiting step of this process. The use of polycations, such as Polybrene, is standard in many retroviral infection protocols owing to the observations of improved infection efficiency. Its mechanism of action is thought to involve neutralization of electrostatic repulsion between virion and cell membranes, enhancing attachment. ViraDuctin™ Retrovirus Transduction Kit is a proprietary formulation for the transduction of retrovirus. After forming a complex with retrovirus in culture medium, the ViraDuctin™ reagents typically provide higher transduction efficiency in many cell types compared to reagents such as Polybrene. It is ideal for transduction of nonpermissive cells such as primary cells and stem cells. 40 transductions.
Echelon Biosciences Research Labs Chymotrypsin like enzyme substrate - 5 mg,
Chymotrypsin like enzyme substrate - 5mg , Succinyl-Leu-Leu-Val-Tyr-AFC Category/Application: Enzyme Substrates This item is non returnable
Waters Corporation Upgrade Kit, Transducer BGM, for HPLC Systems
This upgrade kit is designed to update early 2545 Binary Gradient Modules in HPLC systems. It provides a newer style pressure transducer with a die-cast housing, along with tubing assemblies and an adapter, to replace older, round version transducers.
- Provides one pressure transducer and tubing assemblies.
- Updates early 2545 Binary Gradient Modules.
- Features a newer style transducer with a die-cast housing.
- Replaces older, round version transducers.
- Includes an adapter for installation to the pump head.
- Suitable for HPLC systems.
- Units per package: 1.
Cell Signaling Technology SignalSlide Phospho-Met (Tyr1234/1235) IHC Controls 1 Pack
SignalSlide Phospho-Met (Tyr1234/1235) IHC Controls 1 Pack
Echelon Biosciences Research Labs APP gamma secretase inhibitor - 5 mg, CAS#:
APP gamma secretase inhibitor - 5mg , N-[N-(3,5-difluorophenacetyl)-Ala-S-Phenylglycine Methylester Category/Application: Enzyme Substrates This item is non returnable
Creative Biomart Galsulfase, Human N-acetylgalactosamine 4-sulfatase
The product is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. The product is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular recognition. Post-translational modification of Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and is conserved in all members of the sulfatase enzyme family.
Medchemexpress LLC Syk-IN-1 | 14911150-77-6 | 99.2% | 10 MG
Syk-IN-1 is a potent Syk inhibitor, with an IC50 of 35 nM. This compound is provided as a light yellow to yellow solid and is intended for research use only.
- Potent Syk inhibitor with an IC50 of 35 nM.
- Molecular weight: 366.42.
- Molecular formula: C18H22N8O.
- Appearance: solid.
- Color: light yellow to yellow.
- In vitro solubility: DMSO (100 mg/mL).
- For research use only.