Signal Transduction Reagents and Kits
Neogen Diagnostics K-Blue Luminescent Substrate, 500 ML, HRP, Microwell, Chemiluminescent
K-Blue Luminescent is a stabilized luminescent substrate for use with horseradish peroxidase immunoassays. It contains both luminol and hydrogen peroxide (H2O2) in a two-bottle format with long-term stability, high sensitivity, and excellent signal to noise. Maximal light emission occurs at 430 nm in the presence of peroxidase labeled conjugate. K-Blue Luminescent is compliant with Annex XVII for REACH and contains no hazardous substances at or above published reporting levels. Stable for a minimum of 18-months when stored at 2-8C.
Sigma Aldrich Fine Chemicals Biosciences SANT-1 | 304909-07-7 | MFCD01827306 | 5 mg
SANT-1 | Purity: ≥98% | Mol Wt: 373.49 | 304909-07-7 | MFCD01827306 | 5 mg
BPS Bioscience Inc NFAT EGFP REPORTER LENTIVIRUS
The NFAT eGFP Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. BPS BIOSCIENCE INC mfg# 79922
Cell Biolabs Inc ViraDuctin™ AAV Transduction Kit, 10 transductions
AAV can infect both dividing and non-dividing cells and can be maintained in the human host cell, creating the potential for genome integration. Because AAV is a naturally defective virus, requiring provision of several factors in trans for productive infection, it is considered the safest viral vector to use. The AAV transduction process includes viral binding and entry, intracellular trafficking, nuclear transport, and viral second strand DNA synthesis. The viral second strand DNA synthesis has been shown to be the rate limiting step, which leads to inefficient transduction by AAV vectors. ViraDuctin™ AAV Transduction Kit is a proprietary formulation designed to increase the transduction efficiency of AAV vectors in a variety of cell types. This kit provides the following advantages: (1) Higher transduction efficiency in many cell types, (2) Easy to use, and (3) It is ideal for transduction of nonpermissive cells such as primary cells and stem cells. 10 transductions/kit.
Echelon Biosciences Research Labs GLO-PI(3,4,5)P3BODIPYTMR100ug
BODIPY TMR PI(3,4,5)P3 (BODIPY TMR Phosphatidylinositol 3,4,5-trisphosphate) is a water soluble analog of PI(3,4,5)P3 (PIP3) labeled with the orange fluorophore, Bodipy-TMR, at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. This item is non returnable
Hach Company General Purpose Contacting Conductivity Sensor, Ryton Body, K=10.0 Cell Constant
Nominal Cell Constant (K) = 10.0, 3/4 inch male NPT threaded Ryton body, 6m (20ft) Analog Cable, Graphite Electrode
BPS Bioscience Inc SBE Reporter HEK293 Cell Line, 2 vials of frozen cells, 2 x 10^6 cells in 1 ml of cell freezing medium, ~1.5 x 10^6 cells in 1 ml of 10% DMSO, >1 x 10^6 cells in 1 ml of freezing medium, adherent growth properties
SBE Reporter HEK293 Cell Line, 2 vials of frozen cells, 2 x 10^6 cells in 1 ml of cell freezing medium, ~1.5 x 10^6 cells in 1 ml of 10% DMSO, >1 x 10^6 cells in 1 ml of freezing medium, adherent growth properties
eMolecules 364-98-7 | DIAZOXIDE | AstaTech | MFCD00078578 | 230.670 | C8H7ClN2O2S | 95.000 | CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 | 1g | 302799229
DIAZOXIDE | AstaTech | 364-98-7 | MFCD00078578 | 230.670 | C8H7ClN2O2S | 95.000 | CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 | 1g | 302799229
![Medchemexpress LLC 3-[4-(4-hydroxyphenyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione | 522649-59-8 | 99.7% | 351.4 g/mol | C20H21N3O3 | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235713.png-250.jpg)
Medchemexpress LLC 3-[4-(4-hydroxyphenyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione | 522649-59-8 | 99.7% | 351.4 g/mol | C20H21N3O3 | 25MG
Malic enzyme inhibitor ME1 is a small-molecule probe that selectively inhibits the cytosolic NADP+-dependent malic enzyme 1 (ME1) with an in vitro IC50 of 0.15 μM. Supplied as a high-purity solid, it is intended for use in biochemical and cell-based studies to interrogate ME1-dependent metabolic pathways and related cellular phenotypes.
- Potent ME1 inhibition (IC50 0.15 μM).
- High purity (≈99.7%).
- Available in multiple vial sizes for scalability.
- Suitable for biochemical and cell-based assays.
- Supports mechanistic studies of metabolism and disease.
Medchemexpress LLC Allocryptopine | 485-91-6 | 369.41 | 5 MG
Allocryptopine, a derivative of tetrahydropalmatine, is extracted from *Macleaya cordata* (Thunb.) Pers. Papaveraceae. It has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current. This product is for research use only.
- Has antiarrhythmic effects.
- Potently blocks human ether-a-go-go related gene (hERG) current.
- Purity: 99.53%.
- Structure classification: alkaloids, isoquinoline alkaloids.
Enzo Life Sciences Matrix Metalloproteinase-14 (MMP-14) colorimetric drug discovery kit (1x96wells)
A QUANTIZYME Assay System. The MMP-14 Colorimetric Drug Discovery Kit is a complete assay sytem designed to screen for inhibitors of matrix metalloproteinase-14 (MMP-14, membrane-type matrix metalloproteinase 1, MT1-MMP) using a thiopeptide as a chromogenic substrate. The assays are performed in a convenient 96-well plate format. Also included are active enzyme, a prototypic control inhibitor (NNGH), and a detailed instruction booklet. Alternative name: Membrane type matrix metalloproteinase 1, MT-1 MMP. Applications: Colorimetric detection, HTS Activity assay.
LifeSensors Linkage Profiling UbiTest – Agarose TUBE Elution Kit
The UbiTest kit determines whether a target protein is polyubiquitinated and improves on traditional immunoprecipitation–Western blot methods, which often fail due to epitope masking, reduced antibody affinity, or altered selectivity. By combining immunoprecipitation with broad‑spectrum DUB digestion, the assay reveals increased signal for the protein of interest after DUB treatment, confirming ubiquitination even when untreated samples show weak or no detection. To avoid antibody‑dependent variability, UbiTest uses TUBEs to pull down polyubiquitinated proteins, leveraging their nanomolar affinity and ability to bind all eight linkage types. For linkage determination, LifeSensors employs linkage‑specific DUBs; an increased unmodified band after K48‑ or K63‑specific DUB treatment indicates the protein carries those linkage types.