Caspase-1 substrate. Fluorogenic substrate for caspase-1. AFC has an excitation maximum of 400nm and an emission maximum of 505nm. This product is similar to Ac-YVAD-AMC, ALX-260-024, but the AFC fluorophore has a greater Stokes' shift upon cleavage and the N-terminal is blocked by a benzyloxycarbonyl moiety, which increases cell permeability. Alternative name: Caspase 1 substrate (fluorogenic). Formula: C39H40N5O11F3. MW: 811.8. Purity: ≥95% (HPLC). Single spot (TLC). Solubility: Soluble in DMSO, DMF or methanol; insoluble in water. Long Term Storage: -20°C. Use/Stability: DMF or DMSO stock solution highly stable at -20°C. Handling: Protect from light.