Enzymes and Inhibitors
Medchemexpress LLC Multi-kinase inhibitor 1 | 778274-97-8 | MFCD29035151 | 99.1% | 418.37 g/mol | C20H17F3N4O3 | 5 MG
Multi-kinase inhibitor 1 is a small-molecule research reagent that inhibits multiple tyrosine kinases, including PDGF-R, c-Kit, and Bcr-Abl. It is supplied as an off-white to yellow solid and is used in biochemical and cellular studies to probe receptor tyrosine kinase signaling.
- Potent inhibition of PDGF-R, c-Kit, and Bcr-Abl.
- High purity (99.05%).
- Available as solid and as a 10 mM solution in DMSO.
- Provided with datasheet, SDS, and COA for characterization.
- Molecular formula C20H17F3N4O3; molecular weight 418.37 g/mol.
- Suitable for biochemical and cellular assay applications.
Biotium Coelenterazine HCP
Coelenterazine hcp is a synthetic derivative of coelenterazine. Its aequorin complex generates luminescence intensity 190 times higher and has a faster response time to calcium compared to native coelenterazine.Coelenterazines are luminescent enzyme substrates for apoaequorin and Renilla luciferase. Apoaequorin is used as a calcium indicator. It binds coelenterazine to form an aequorin complex that emits light upon calcium binding and measures concentrations ~0.1 uM to >100 uM. Renilla luciferase is widely used as a reporter of transcription regulation and as a donor in bioluminescence resonance energy transfer (BRET) to study protein-protein interactions. Coelenterazines are also used for chemiluminescent detection of superoxide anions and peroxynitrite in cells or tissues. Coelentrazine analogs and water-soluble Aquaphile™ Coelenterazines are also available.Properties : Yellow solid soluble in MeOH or EtOH; Store at -20°C, protect from light; C25H25N3O2; MW: 399.49.
Carnabio Usa Inc IKKB(IKBKB)/10UG/TRUNCATED
IKK(IKBKB), Truncated protein, Wild type, Amino Acid 1-662 , NP_001547.1, Expressed in Insect (sf21); 10microg
Grainger Insulated Beverage Server Satin 34 oz
The Spring USA 16W674 Insulated Beverage Server is a stainless steel beverage dispenser with a 2.5 gallon capacity. It features vacuum insulation to keep beverages hot or cold. The dispenser has a push button spigot, removable lid, and sturdy handle for easy pouring and transport. It can hold coffee, tea, lemonade, punch and other beverages for gatherings and events. This commercial grade dispenser is made in the USA.
Biotium Chromogenic beta-galactosidase Substrate sampler kit
For researchers wishing to investigate the suitability of our various chromogenic -galactosidase substrates, this sampler kit provides 5 mg each of the following five different substrates: X-Gal, Red-D-Gal, Rose--D-Gal, Purple--D-Gal, and Green--D-Gal.
AG Scientific Inc Pyruvate Oxidase 1 KU
Pyruvate oxidase is originated from Aerococcus viridans and used as a component of screen-printed phosphate biosensor for monitoring phosphate concentrations in a sequencing batch reactor (SBR) system. It consumes phosphate in the presence of pyruvate and oxygen and generates hydrogen peroxide, carbon dioxide and acetylphosphate. The enzyme is a flavoprotein with the relatively tightly bound cofactors flavin adenine dinucleotide, thiamine pyrophosphate, and a divalent metal ion, with Mn2+ being the most effective.Activity: 40 units/mg powderOne unit is defined as amount of enzyme required to generate 1 μmol of H2O2 per minute at 37°C, pH 6.5.
Carnabio Usa Inc CAMK1B(PNCK)/5UG/FULL-LENGTH
CaMK1(PNCK), Full-length, Wild type, Amino Acid 1-343, Q6P2M8, Expressed in Insect (sf21); 5microg
New England Biolabs, Inc. PstI-HF – 10000 units
A high fidelity restriction endonuclease that recognizes the sequence C_TGCA^G. High Fidelity (HF) Restriction Enzymes have 100% activity in rCutSmart Buffer; single-buffer simplicity means more straightforward and streamlined sample processing. HF enzymes also exhibit dramatically reduced star activity. HF enzymes are all Time-Saver qualified and can therefore cut substrate DNA in 5-15 with the flexibility to digest overnight without degradation to DNA. Engineered with performance in mind, HF restriction enzymes are fully active under a broader range of conditions, minimizing off-target products, while offering flexibility in experimental design. NEB extensively performs quality controls on all standard and high-fidelity (HF) restriction enzymes.
New England Biolabs, Inc. BstAPI – 200 units
A restriction endonuclease that recognizes the sequence GCAN_NNN^NTGC.
New England Biolabs, Inc. DNase I-XT-1000 units
An engineered variant of DNase I DNase I-XT is a salt-tolerant DNA endonuclease that nonspecifically cleaves DNA to release di- tri- and oligonucleotide products with 5 prime phosphorylated and 3 prime hydroxylated ends. DNase I-XT acts on single- and double-stranded DNA chromatin and the DNA strand of RNADNA hybrids. While DNase I (M0303) is inhibited by salt concentrations greater than 50 mM DNase I-XT exhibits optimal activity between 50-100 mM salt and retains 65% and about 40% activity in 200 and 300 mM salt respectively. This increased salt tolerance makes DNase I-XT the preferred enzyme for DNA template removal from an in vitro transcription (IVT) reaction. Importantly DNase I-XT is RNase-free allowing for the complete removal of DNA from RNA preparations while maintaining RNA integrity.
New England Biolabs, Inc. Msz Exonuclease I - 1000 units
A DNA specific exonuclease isolated from Methylocaldum szegediense that catalyzes the removal of nucleotides from linear single-stranded DNA in the 3 prime to 5 prime direction with optimal activity between 45 and 60 degrees C. Isolated from a strain of E. coli which carries the cloned pMC45-1 gene from Methylocaldum szegediense.
Carnabio Usa Inc JAK3/5UG/CATALYTIC
JAK3, Catalytic domain, Wild type, Amino Acid 795-1124, NP_000206.2, Expressed in Insect (sf21); 5microg
ACROBiosystems GENIUS™ Pro Nuclease is a tag free recombinant form of Serratia marcescens extracellular endonuclease produced in Escherichia coli cells using a proprietary process at ACRObiosystems. GENIUS™ Pro Nuclease is a homodimer with monomer molecul
GENIUS™ Pro Nuclease is a tag free recombinant form of Serratia marcescens extracellular endonuclease produced in Escherichia coli cells using a proprietary process at ACRObiosystems. GENIUS™ Pro Nuclease is a homodimer with monomer molecul
New England Biolabs, Inc. Induro Reverse Transcriptase - 4000 units
Induro Reverse Transcriptase is a group II intron-encoded RT that exhibits increased thermostability high processivity and increased tolerance of inhibitors in the synthesis of cDNA from RNA. It is an ideal enzyme for challenging cDNA synthesis reactions from long transcripts RNAs with strong secondary structures and RNA samples with inhibitors. Additionally Induro Reverse Transcriptase supports RNA-seq applications such as long-read RNA sequencing.