Modifying Enzymes
INTACT GENOMICS INC Taq DNA Ligase 10,000 Units
Taq DNA Ligase catalyzes the formation of a phosphodiester bond in duplex DNA containing adjacent 5′-phosphoryl and 3′-hydroxyl termini, using NAD+ as a cofactor. The ligation will occur only if the oligonucleotides are perfectly paired to the complementary target DNA and have no gaps between them; therefore, a single-base substitution can be detected. This product is active at elevated temperatures (45°C-70°C) (1, 2).Applications Allele-specific gene detection by using Ligase Detection Reaction (LDR) and Ligase Chain Reaction (LCR) (1). Mutagenesis by incorporation of a phosphorylated oligonucleotide during primer extension amplification(3).
INTACT GENOMICS INC Cas12a Nuclease 40 µg
ApplicationsIntact Genomics (ig) Cas12a Nuclease is the purified recombinant Francisella tularensis Cas12a enzyme for in vitro editing. This enzyme is designed to perform CRISPR/Cas12a-mediated genome editing. The physical purity of this enzyme is ≥65% as assessed by SDS-PAGE with Coomassie blue staining and densitometry.Product Components: Cas12a Nuclease 10x Cas12a Nuclease Reaction Buffer
INTACT GENOMICS INC RNase Inhibitor, Murine (Glycerol-free) 5,000 Units
Intact Genomics (ig) Glycerol-free RNase Inhibitor is a 49.8 kDa recombinant protein of murine origin which inhibits RNases A, B and C by binding noncovalently in a 1:1 ratio with high affinity. Moreover, it does not inhibit polymerase activity when used with Taq DNA Polymerase, Reverse Transcriptase. Glycerol-free RNase Inhibitor from Murine is resistant to oxidation compared to the human/porcine RNase inhibitors as it lacks a pair of cysteine residues found in the human/porcine versions. Stable at less than 1 mM DTT.Benefits of Glycerol-Free Enzyme: Optimal for Lyophilization ensuring stability and performance for point-of-care tests like molecular diagnostics. Better Compatibility: Avoids interference. Improved Performance: Enzyme formulations are less viscous. Simplified Integration: Allows for more flexible formulation.Applications: cDNA synthesis RT-PCR/RT-qPCR In vitro transcription RNA labeling Microfluidics assays
Supelco Inc HYALURNIDSE SHEEP TYPEII 100MG
Hyaluronidase, Type II, lyophilized powder, A%Y300A units/mg solid
New England Biolabs, Inc. TaqI Methyltransferase – 1000 units
TaqI Methyltransferase modifies the adenine residue (N6) of the sequence TCGA.
Cayman Chemical N-Oleoyl-L-SerIn 1mg
An endogenous lipid that has been reported to stimulate bone formation and to inhibit bone resorption
Cayman Chemical Oleoyl-L-carnItIn 10mg
A long-chain acylcarnitine and GlyT2 inhibitor (IC50 = 340 nM); selective for GlyT2 over GlyT1 (IC50 = >10,000 nM); plasma levels are increased in patients with chronic kidney disease or end-stage renal disease receiving incident hemodialysis and these are associated with cardiovascular mortality