Custom Peptides
Cayman Chemical ChenodeoxycholylputrescIn 10mg
A polyamine bile amidate; has been found in lion, but not mouse, fecal samples; has been used as a standard in the detection of chenodeoxycholyl-putrescine in mammalian intestinal and fecal samples
Cayman Chemical BIalaphosodIum salt 10mg
A natural non-selective phytotoxin that is converted in vivo to the active agent phosphinothricin, which inhibits glutamine synthetase (Ki = 6.1 µM); used in the selection of transgenic plants that express the bar gene, usually under the control of a constitutively active viral promoter
Cayman Chemical 3 4MethylendIoxyaPyrrolId 10mg
An analog of 3,4-MDPV that differs only by the addition of a single carbon to the alkyl chain; intended for forensic and research applications
Cayman Chemical DImethoate-d6 10mg
An internal standard for the quantification of dimethoate by GC- or LC-MS
Cayman Chemical StevIosIdehydrate 10mg
A natural non-caloric sweetener; increases glucose-stimulated insulin secretion in isolated mouse pancreatic islets at 1 µM; reduces LPS-stimulated increases in TNF-α and IL-1β production in THP-1 cells, but also induces TNF-α and IL-1β production in unstimulated THP-1 cells at 1 mM; decreases systolic blood pressure in GK type 2 diabetic rats at 0.03 g/kg; reduces TPA-induced EAr edema in mice (ID50 = 291.6 UG/ear)
Cayman Chemical nastrozole 10mg
An aromatase/CYP19A1 inhibitor (IC50 = 15 nM for human placental aromatase/CYP19A1); selective for aromatase/CYP19A1 over CYP1A2, CYP2A6, CYP2C9, CYP2D6, and CYP3A (IC50s = 27-650 μM); blocks ovulation in mature female rats and androstenedione-stimulated uterine development in pubertal female rats at 0.1 mg/kg; inhibits peripheral aromatase/CYP19A1 and reduces plasma estradiol concentrations in male pigtailed monkeys at ≥0.1 mg/kg; reduces tumor incidence and the number of tumors well as increases latency to tumor appearance in a rat model of premenopausal mammary tumorigenesis at 0.5 mg/kg
Cayman Chemical nacardIc AcId 10mg
An alkyl salicylic acid isolated from cashew shells; inhibits the HAT activity of p300 and PCAF (IC50 = 8.5 and 5 µM, respectively); suppresses NF-κB activation, inhibits IκBα phosphorylation, and prohibits p65 nuclear translocation
Cayman Chemical MetIprnolol 10mg
A β-AR antagonist; binds to primary rabbit iris and ciliary body homogenates (Ki = 34 nM); inhibits isoproterenol-induced relaxation in guinea pig atrium and fenoterol-induced relaxation in rat uterus (pA2s = 8.3 and 8.4, respectively); inhibits anoxia-induced cell death in primary rat retinal cells and sodium nitroprusside-induced lipid peroxidation in rat primary retinal homogenates (100 μM); decreases α-chymotrypsin-induced increases in IOP in rabbits when administered topically to the eye at a dose of 0.3%; inhibits the blinking response to ocular tactile stimulation in rabbits when administered topically to the eye at a dose of 0.6%
Cayman Chemical DIclofensInhydrochlorIde 10mg
A potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively; intended for research and forensic applications
Cayman Chemical CynIdIn 3-OD-Galactopyrn 10mg
An anthocyanin flavonoid with antioxidant properties; scavenges radicals in DPPH, TEAC, ORAC, and hydrogen peroxide assays; decreases the release of LDH and the activation of caspase-3 in lymphocytes with t-butyl hydroperoxide-induced oxidative damage
Cayman Chemical Nacetyl3 4MethylendIoxyme 10mg
An acetylated analog of methylone, the MDMA-type designer drug that has been detected in products marketed as bath salts, plant food, and tablets; intended for forensic and research purposes
Cayman Chemical PalustrIc AcId 10mg
A diterpenoid with diverse biological activities; increases secreted hydrogen peroxide levels in isolated mouse macrophages at 2 mg/ml; toxic to water fleas and rainbow trout (LC50s = 0.1 and 0.5 mg/L, respectively); phloem levels are increased in mechanically injured, as well as mechanically injured and L. abietinum-infected, red pine and white spruce trees; has been found as an environmental contaminant in pulp and paper mill effluent