Custom Peptides
Cayman Chemical ThymulInacetate hydrate 10mg
A peptide hormone; primarily produced by thymic epithelial cells; potentiates mitogen-induced proliferation of IL-2 receptor-positive mature T cells; has anti-inflammatory effects in various rodent models of inflammation; suppresses autoantibody production in a mouse model of reovirus-induced thyroiditis; prevents endotoxin-induced hyperalgesia in rats
Cayman Chemical Morus rot Kuwnon C 10mg
A prenylated flavone; scavenges DPPH radicals (EC50 = 72.99 UG/ml); active against E. coli, S. typhimurium, S. epidermis, and S. aureus (MICs = 10, 25, 6.25, and 6.25 UG/ml, respectively); inhibits the growth of P388 mouse lymphoma cancer cells (IC50 = 14 UG/ml); improves motor coordination in a rotarod test and decreases neuronal loss in the substantia nigra pars compacta in a mouse model of MPTP-induced Parkinson's disease at 30 mg/kg
Cayman Chemical Cornus ofcnals Verbenaln 10mg
An iridoid glucoside; inhibits the activities of COX-1 and COX-2 by 37 and 48%, respectively, at 258 µM; inhibits proliferation of AGS gastric, SF-268 CNS, HCT116 colon, NCI H460 lung, and MCF-7 breast cancer cells at 129 µM; reduces carrageen-induced paw edema and TPA-induced EAr dema in mice; reduces increases in MDA levels and ROS production in isolated brain mitochondria isolated from, as well as decreases infarct volume and neurological deficits in, a rat model of MCAO-induced ischemia-reperfusion injury
Cayman Chemical BetulnIc ACD propargyl St 10mg
An alkyne derivative of betulinic acid; has been used in click chemistry reactions for the synthesis of cytotoxic anticancer betulinic acid derivatives
Cayman Chemical 11-hydroxy EtIocholnolon 10mg
A metabolite of hydrocortisone; fecal levels are increased in response to environmental stress in giraffes and plains zebras
Cayman Chemical GenIposIdIc AcId 10mg
An iridoid glycoside with diverse biological activities; inhibits TPA-induced EAr edema in mice by 91.01% when administered topically at 0.1 mg/ear; increases survival rate, attenuates increases in ALT activity and TNF-α levels in serum, as well as hepatic levels of MDA, and prevents decreases in hepatic GSH levels in a mouse model of fulminant hepatic failure induced by D-galactosamine and LPS at 50 mg/kg; decreases systolic blood pressure and heart rate and increases plasma levels of ANP in spontaneously hypertensive rats at 100 mg/kg
Cayman Chemical 4Hydroxy1 2phenylethylpI 10mg
A building block; has been used in the synthesis of ligands of the mAChR or σ1 receptor; a metabolite of furanyl fentanyl and FIBF
Cayman Chemical 7ahydroxy DehydroepIndROS 10mg
An active metabolite of dehydroepiandrosterone; formed from dehydroepiandrosterone via 7-hydroxylation by CYPs; increases antigen-induced production of anti-tetanus toxoid and anti-pertussis antigen IgGs in co-cultures of human tonsil-derived B and T cells at 1 µM; increases serum concentrations of anti-lysozyme IgG in mice at 6.25 mg/kg
Cayman Chemical AdenylosuccInIc ACDamonIu 10mg
A purine nucleotide and an intermediate in the purine nucleotide cycle; converted into AMP and fumarate by ADSL in the cytosol; inhibits calcium-induced activation of non-selective cation channels in isolated rat brown adipocytes in a patch-clamp assay at 10 µM; induces contractions in isolated guinea pig uterus strips at 100 µM; increases glucose-induced insulin exocytosis in INS-1 832/13 insulinoma cells at 10 µM; decreases muscle damage and pseudohypertrophy in a dystrophin-deficient mdx mouse model of DMD
Cayman Chemical TrIptophenolIde 10mg
A diterpenoid with antiandrogenic activity; an antagonist of wild-type and mutant ARs (IC50s = 260, 388, 480, and 437 nM for wild-type, ART877A, ARF876L, and ARW741C/T877A, respectively, in transactivation assays); inhibits the growth of, and reduces AR levels in, LNCaP prostate cancer cells at 5 µM
Cayman Chemical PropIophenon 10mg
An analytical reference standard categorized as a precursor in the synthesis of cathinones; intended for research and forensic applications
Cayman Chemical NBenzylcyclohexylamInhydr 10mg
An analytical reference standard categorized as an arylcyclohexylamine; has been found as a cutting agent in 3,4-MDMA samples; intended for research and forensic applications
Cayman Chemical Fenclofenac 10mg
An NSAID and COX inhibitor (IC50s = 7 and 4 µM for COX-1 and COX-2, respectively); reduces paw volume in a rat model of adjuvant-induced polyarthritis at 3, 15, and 75 mg/kg; induces antinociception in rats (ED50 = 54.3 mg/kg); reduces carrageenan-induced paw edema in rats at 20-180 mg/kg