Custom Peptides
Cayman Chemical 1 2DIarachIdonylsnglycero 10mg
A phospholipid containing the polyunsaturated long-chain (20:4) arachidonic acid inserted at the sn-1 and sn-2 positions
Cayman Chemical C18 CeramIded18 118 0 10mg
A bioactive sphingolipid; the primary short-chain ceramide found in brain tissue; synthesis is regulated by Lass1 in mice; positively correlated to body mass index and inversely related to insulin sensitivity; reduces cell growth in UM-SCC-22A squamous cell carcinoma cells; selectively downregulated in 32 squamous cell carcinoma tumor tissues; positively correlated to body mass index and inversely related to insulin sensitivity in type 2 diabetic patients
Cayman Chemical 12methyl TrIDcnoIc ACD me 10mg
A methylated fatty acid methyl ester; has been found in beef tallow, mutton tallow, and cod liver oil; has been used as a standard for the quantification of 12-methyl tridecanoic acid in the triglyceride fraction of skin surface lipids from human males by GC-MS
Cayman Chemical TIgloylLcarnItInchLRIde 10mg
A short-chain acylcarnitine; plasma levels are increased in several melanoma mouse xenograft models compared with non-tumor bearing mice; levels are increased in dried blood spots from neonates with T2 deficiency, an inborn error of isoleucine metabolism characterized by ketoacidosis
Cayman Chemical Vesnarnon 10mg
A PDE3 inhibitor and ERG1 channel blocker (IC50s = 10.7, 13.2, and 1.1 μM for PDE3A, PDE3B, and ERG1, respectively); increases contractile tension in isolated ventricular muscles of dog, cat, rabbit, and guinea pig in a dose-dependent manner; increases right ventricular pressure with no effect on heart rate in dog models of tricuspid insufficiency- and pulmonary stenosis-induced congestive heart failure; increases contractility and coronary flow while decreasing heart rate in a guinea pig model of aortic stenosis-induced congestive heart failure
Cayman Chemical TesaglItazar 10mg
A dual agonist of PPARα and γ (IC50s = 1 and 0.2 µM, respectively) that at 3 µM/kg/day for 3 weeks has been used to reduce insulin resistance in obese Zucker rats
Cayman Chemical CyclothIazIde 10mg
A benzothiadiazide that acts as a potentiator of AMPA receptors, positively modulating its response to glutamic acid (EC50 = 3.8 µM); also a negative modulator of GABAA receptors, reversibly inhibiting both evoked and spontaneous inhibitory postsynaptic currents (IC50 = 58 µM)
Cayman Chemical SLP7111228hydrochlorIde 10mg
A potent and selective SPHK1 inhibitor (Kis = 0.048 and >10 μM for SPHK1 and 2, respectively); induces a concentration-dependent decrease in U937 cells; decreases blood levels of S1P in a dose-dependent manner in rats
Cayman Chemical 4 5 7-TrImethoxyflavon 10mg
A flavonoid with diverse biological activities; inhibits AChE and BChE by 47.1 and 46.2%, respectively, in a cell-free assay at 0.1 mg/ml; scavenges radicals in a TEAC assay at 1 and 10 µM; inhibits RANKL-induced osteoclastic differentiation of RAW 264.7 cells at 10 µM; stimulates chloride secretion in Calu-3 cells
Cayman Chemical ProstaglndIn Bx 10mg
PGBx is a mixture of oligomers of PGB1 with a molecular weight of 1,000-1,500. It has antioxidant and free radical trapping activity that was first studied in isolated mitochondria.{477} PGBx has anti-inflammatory and cytoprotective activity which may be attributed to inhibition of the 14 kDa sPLA2.{414,1188} At a dose of 1 mg/kg, PGBx significantly reduces the incidence of ulcers in rats.{414}
Cayman Chemical MalntIdetrIfluoroacetAT s 10mg
A fluorescent substrate for PKA and PKC; upon phosphorylation by PKA or PKC, the intrinsic tyrosine fluorescence decreases and can be used to quantify PKA and PKC activity; ex/em = 285/302 nm
Cayman Chemical TerbuthylazIn 10mg
A triazine herbicide; active against a variety of broadleaf and grass weeds in combination with S-metolachlor; has been found in surface groundwater and soil samples
Cayman Chemical 3-demethyl ColchIcIn 10mg
An active metabolite of colchicine; suppresses antibody production induced by sheep red blood cells in co-culture with isolated mouse spleen cells from 0.1-10 UG/ml; inhibits carrageenan-induced paw edema in rats at 100 UG/animal
