Nucleic Acid Synthesis
AURORA BIOLABS LLC Kras Q61K, GST-tag, GDP Loaded,100
Kras is a member of the RAS protein family, which are a class of small GTPases involved in cell signaling. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner. The protein also contains mutation of interested Q61K loaded with GDP. Ready for use in the GDP/GTP exchange assay or as a negative control for Kras-RAF interaction.
Apexbio Technology LLC SpCas9 mRNA (ARCA 5mCTP ψUTP) 1mg (1mg/mL)
SpCas9 mRNA (ARCA 5mCTP UTP) encodes Streptococcus pyogenes Cas9 (SpCas9) protein This product can be used with purified guide RNA (gRNA) sequences in the CRISPR/Cas system for recognizing and cleaving genomic DNA targets CRISPR/Cas a defense system has been adapted from the Type II CRISPR/Cas system of S pyogenes for eukaryotic gene editing It requires two key components the Cas9 endonuclease and a non-coding gRNA Guided by a single gRNA Cas9 introduces DNA double-strand breaks (DSBs) at specific genomic sites Cells activate endogenous DNA repair pathways non-homologous end joining (NHEJ) or homology-directed repair (HDR) to repair the targeted DSB SpCas9 mRNA (ARCA 5mCTP UTP)is designed to mimick mature eukaryotic mRNA It contains a cap 0 structure generated via co-transcriptional capping Incorporation of modified nucleotides 5mCTP UTP poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Medchemexpress LLC Fludarabine triphosphate trisodium | 100.0% | 591.12 | C10H12FN5Na3O13P3 | 5 MG
Fludarabine triphosphate trisodium is the active triphosphate metabolite of fludarabine that inhibits DNA primase and interferes with DNA synthesis. It blocks primer RNA formation, inhibits ribonucleotide reductase and DNA polymerase, and promotes apoptosis in susceptible cells. Supplied as a colorless to light-yellow high-purity liquid for research applications.
- Potent, noncompetitive inhibitor of DNA primase.
- Blocks primer RNA formation and DNA synthesis.
- Inhibits ribonucleotide reductase and DNA polymerase.
- High reported purity suitable for analytical work.
- Liquid form for rapid dissolution and use.
- Requires protected, low-temperature storage to maintain stability.
Supply Solutions Roche - ATP; lithium salt; pkg of 400 uL (4,000 cm2 membrane)
Roche - ATP; lithium salt; pkg of 400 uL (4,000 cm2 membrane)
BIORTUS USA INC Human KRAS4B Protein, biotinylated/GDP_loaded, 100UG
Gene Name: KRAS. Uniprot: P01116. Construct: biotinylated-Avi-KRas4B(T2-M188 end) (G12D),GDP loaded. Expression Host: E. coli. Purity: 90%.
Sigma Aldrich Fine Chemicals Biosciences Guanosine 3',5'-cyclic monophosphate sodium salt >=99% (HPLC), powder | 40732-48-7 | MFCD00038424 | 250MG
Guanosine 3',5'-cyclic monophosphate sodium salt >=99% (HPLC), powder | Purity: >=99% (HPLC) | Mol Wt: 367.19 | 40732-48-7 | MFCD00038424 | 250MG
![Revvity Health Sciences Inc UTP, [α-<sup>32</sup>P]- 800Ci/mmol 20mCi/ml EasyTide, 250 µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00001872-502099600.JPG-250.jpg)
Revvity Health Sciences Inc UTP, [α-32P]- 800Ci/mmol 20mCi/ml EasyTide, 250 µCi
UTP, [α-32P]- 800Ci/mmol 20mCi/ml EasyTide, 250 µCi
Enzo Life Sciences ODN M362 (TLRGRADE™) (synthetic) (BULK) (1mg)
CpG oligodeoxynucleotide (Type C) with phosphorothioate backbone. Specific ligand for TLR9 (Toll-like receptor 9). Formulation: Lyophilized. Sterile. Long Term Storage: +4°C.
Enzo Life Sciences ODN 2118 (TLRGRADE™) (synthetic) (Control) (100µg)
GpC oligodeoxynucleotide with mixed phosphodiester/phosphorothioate backbone. Formulation: Lyophilized. Sterile. Long Term Storage: +4°C.
Enzo Life Sciences Dual-iODN (class I) (endotoxin-free) (synthetic) (100µg)
Inhibitory iODN oligodeoxynucleotide with phosphorothioate backbone. Sequence of an inhibitory ODN for in vivo use in rodents (50-150µg per injection): prototype class I that potently inhibits TLR9 and TLR7 signaling. Formulation: Lyophilized. Sterile. Long Term Storage: +4°C.
Medchemexpress LLC 3-Methyluridine | 2140-69-4 | 99.1% | 258.23 | 25 MG
3-Methyluridine | 2140-69-4 | 99.1% | 258.23 | 25 MG
Cambridge Isotope Laboratories 5-Methyluridine 5-triphosphate ammonium salt (ribose-1 2 3 4 5-13C5 99%) (in solution) CP 95% 100 umol
5-Methyluridine 5-triphosphate ammonium salt (ribose-1 2 3 4 5-13C5 99%) (in solution) CP 95% 100 umol