Nucleic Acid Synthesis
Medchemexpress LLC Trifluridine/tipiracil hydrochloride mixture | 733030-01-8 | 99.98% | 435.76 | 100 MG
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. It is a 1:0.5 molar mixture of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). This mixture primarily exhibits its antitumor activity by inhibiting thymidylate synthase (TS) and incorporating into DNA. It prevents body weight loss and reduces relative tumor volume in colorectal cancer and gastric cancer mouse models.
- Potent and orally active nucleoside antitumor agent.
- Composition: 1:0.5 molar mixture of FTD and TPI.
- Mechanism of action: inhibition of thymidylate synthase (TS) and incorporation into DNA.
- Prevents body weight loss and reduces relative tumor volume in colorectal cancer and gastric cancer mice models.
Medchemexpress LLC HY-10586 500mg Medchemexpress, 5-Azacytidine Ladakamycin;5-AzaC;Azacitidine CAS:320-67-2 Purity:98%
Medchemexpress,HY-10586 500mg 5-Azacytidine Ladakamycin;5-AzaC;Azacitidine CAS:320-67-2 Formula:C8H12N4O5 5-Azacytidine is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC FITC-labeled ODN 1018 sodium | DNA, d(P-thio)(T-G-A-C-T-G-T-G-A-A-C-G-T-T-C-G-A-G-A-T-G-A), sodium salt | 1 MG
FITC-labeled ODN 1018 (sodium) is an oligodeoxynucleotide that acts as a TLR-9 agonist.
- Evaluates CpG ODN cellular uptake.
- Evaluates CpG ODN localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.