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2'-O-Methyluridine is a modified nucleoside that can be found in *T. thermophile* tRNA. Its level in serum is decreased in patients with breast cancer. It can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which decreases ApoB protein levels in HepG2 and prevents IFN-α production in isolated human PBMCs.
Found in *T. thermophile* tRNA
Decreased serum levels in breast cancer patients
Can be incorporated into siRNA
Decreases ApoB protein levels in HepG2
Prevents IFN-α production in isolated human PBMCs
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Nucleoside-Analog-1 is a click chemistry reagent containing an azide group. It can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups, and in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Click chemistry reagent containing an azide group.
Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups.
Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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5-Methylcytidine is a nucleoside compound with antiviral activity, showing an IC50 against HSV-1 of 0.06 μM. It is also a common modification form in DNA, playing a role in gene expression regulation and development, and is associated with diseases like cancer.
Nucleoside compound
Antiviral activity against HSV-1
Common DNA modification
Involved in gene expression regulation and development
Related to disease occurrence and development, such as cancer
Potential for research in antiviral therapies
Useful for studying gene expression regulation and DNA modifications
Relevant for cancer research
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6-Methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents.
Uridine analogue
Potential antiepileptic effects
Used to study anticonvulsant and anxiolytic activities
Used to develop new antihypertensive agents
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2′-O-Methyluridine is a modified nucleoside found in T. thermophile tRNA. Its serum level is decreased in breast cancer patients. It can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which reduces ApoB protein levels in HepG2 and prevents IFN-α production in isolated human PBMCs.
Modified nucleoside
Found in T. thermophile tRNA
Decreased in serum levels in breast cancer patients
Used in siRNA targeting apolipoprotein B
Reduces ApoB protein levels
Prevents IFN-α production
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Medchemexpress, HY-W009444 1g 5-Methyluridine CAS:1463-10-1 5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. It is composed of a 1:0.5 molar mixture of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). The antitumor activity primarily stems from its inhibition of thymidylate synthase (TS) and its incorporation into DNA.
Potent and orally active nucleoside antitumor agent
Composed of a 1:0.5 molar mixture of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI)
Inhibits thymidylate synthase (TS)
Incorporates into DNA for antitumor activity
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