Nucleosides
Sigma Aldrich Fine Chemicals Biosciences Cytidine 5'-diphosphocholine sodium salt hydrate >=99.0% (HPLC) | 33818-15-4 (anhydrous) | MFCD00150508 | 250MG
Cytidine 5'-diphosphocholine sodium salt hydrate >=99.0% (HPLC) | Purity: >=99.0% (HPLC) | 33818-15-4 (anhydrous) | MFCD00150508 | 250MG
Apexbio Technology LLC Telbivudine 3424-98-4 10mg
Telbivudine (3424-98-4) is a small-molecule inhibitor targeting hepatitis B virus (HBV) DNA polymerase reverse transcriptase It is designed to inhibit viral replication by incorporating into HBV DNA after intracellular phosphorylation resulting in chain termination Telbivudine exerts its biological activity primarily through selective inhibition of HBV DNA polymerase reverse transcriptase In biochemical assays telbivudine demonstrates antiviral inhibition with an IC50 value typically ranging between 0 2 to 0 5 M Based on these pharmacological properties telbivudine holds research potential in studies of HBV biology mechanisms of antiviral resistance and the development of novel therapeutic strategies
![Medchemexpress LLC 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione | 69123-98-4 | MFCD00866922 | 99.9% | 372.09 | C9H10FIN2O5 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000226830.png-250.jpg)
Medchemexpress LLC 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione | 69123-98-4 | MFCD00866922 | 99.9% | 372.09 | C9H10FIN2O5 | 1 ML
Fialuridine (FIAU) is a fluorinated, iodinated nucleoside analog with demonstrated antiviral activity supplied for laboratory research. The product is offered as a ready-to-use 10 mM solution in DMSO (1 mL) and as solid quantities for use in synthesis and biological testing.
- Antiviral nucleoside analog active against hepatitis B virus and herpesviruses.
- Supplied as 10 mM solution in DMSO (1 mL) for immediate use in assays.
- Also available in multiple solid sizes for formulation or synthesis.
- High reported purity (≈99.9%) suitable for research applications.
- Molecular formula C9H10FIN2O5; molecular weight 372.09 Da.
Cayman Chemical 6-thIo-2-DeoxygunosIn 5mg
A purine nucleoside analog; reduces infection of Calu-3 cells by SARS-CoV-2 (EC50 = 0.04 µM) but is also toxic to Calu-3 cells (CC50 = 1.14 µM); decreases tumor volume and increases the number of tumor cells with telomere dysfunction-induced foci in an A549 NSCLC mouse xenograft model at 2 mg/kg; increases the number of PD-1+ CD8+ T cells, as well as induces tumor regression when administered in combination with anti-PD-L1 in MC-38 murine colon carcinoma models
Chem-Impex International, Inc. Adenosine-5'-diphosphate potassium salt | 72696-48-1 | MFCD00066472 | 5G
Adenosine-5'-diphosphate potassium salt, 72696-48-1, MFCD00066472, 5G
Chem-Impex International, Inc. Inosine-5'-diphosphate trisodium salt | MFCD00043058 | 100MG
Inosine-5'-diphosphate trisodium salt, MFCD00043058, 100MG
Chem-Impex International, Inc. Uridine | 58-96-8 | MFCD00006526 | 25G
Uridine, 58-96-8, MFCD00006526, 25G
Cayman Chemical ANTIBODY ThIo-TEPA 500mg
An alkylating agent with anticancer activity (IC50 = 1.5 μM against P388 murine leukemia cells); alkylates DNA and inhibits thymidine incorporation (IC50 = 2 μM) inducing irreversible DNA damage; crosslinks guanine nucleotides and induces cell cycle arrest via the formation of interstrand cross-links in L1210 and MCF-7 cancer cells in vitro; reduces the number of pulmonary metastases in mice following subcutaneous injection of melanoma cells; decreases the number of postoperative lung metastases when administered at a dose of 10 mg/kg after surgical removal of an S-91 melanoma tumor established via intramuscular injection in mice
Medchemexpress LLC 3-Methylcytidine | 2140-64-9 | 99.3% | 257.24 | 100 MG
3-Methylcytidine is a urinary nucleoside that can serve as a biomarker for four types of cancer, including lung cancer, gastric cancer, colon cancer, and breast cancer. Studies have shown it to be significantly upregulated in the urine samples of breast cancer patients, indicating its potential utility in diagnostic applications.
- Biomarker for lung, gastric, colon, and breast cancers
- Upregulated in urine samples of breast cancer patients
- Urinary nucleoside
![Revvity Health Sciences Inc Guanosine 5'-triphosphate, [8-<sup>3</sup>H], (GTP,[<sup>3</sup>H])](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502105566.jpg-250.jpg)
Revvity Health Sciences Inc Guanosine 5'-triphosphate, [8-3H], (GTP,[3H])
Guanosine 5'-triphosphate, [8-3H], (GTP,[3H])
Alkali Scientific Cytidine, 500 G
Cytidine is a pyrimidine nucleoside consisting of cytosine linked to a ribose sugar and is a key building block of RNA molecules. It plays a vital role in nucleic acid metabolism, RNA synthesis, and cellular biochemical processes. In molecular biology research, cytidine is frequently used in studies examining RNA transcription, nucleotide metabolism, and enzymatic reactions involving nucleosides. Scientists utilize cytidine in biochemical assays to investigate nucleic acid synthesis, cellular regulation, and metabolic pathways related to nucleotide turnover. Because of its importance in RNA structure and function, cytidine is widely used in life science laboratories for nucleic acid research, molecular biology experiments, and biochemical pathway analysis.
Medchemexpress LLC 2'-O-Methyluridine-d3 | 2140-76-3 | 99.2% | 261.25 | 1 MG
2'-O-Methyluridine-d3 is deuterium labeled 2'-O-Methyluridine (HY-W011824). 2'-O-Methyluridine is a modified nucleoside found in *T. thermophile* tRNA. It can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which decreases ApoB protein levels in HepG2 and prevents IFN-α production in isolated human PBMCs. The level of 2'-O-Methyluridine in serum is decreased in patients with breast cancer. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Pseudouridine | 1445-07-4 | 99.9% | 244.20 | 10 MG
Pseudouridine is an isomer of uridine and the most abundant modified nucleoside found in non-coding RNA. It plays a crucial role in fine-tuning and stabilizing regional structures in rRNA and tRNA, which are essential for their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments show potential for inhibiting aberrant protein synthesis and are promising for research related to myelodysplastic syndrome (MDS)-related leukemia.
- Isomer of uridine and most abundant modified nucleoside in non-coding RNA.
- Fine-tunes and stabilizes regional structures in rRNA and tRNA.
- Essential for mRNA decoding, ribosome assembly, processing, and translation.
- Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis.
- Holds promise for research on myelodysplastic syndrome (MDS)-related leukemia.
Abcam Resorufin b-D-glucopyranoside, 10MG
MW 375.3 Da, Purity >95%. Stable β-glucosidase probe (470nm). Releases the red fluorescent dye resorufin M0202 upon β-glucosidase enzyme cleavage. Successful in numerous applications in cell biology, high-throughput and high-content screening and diagnostics.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences 5-Methylcytidine >=99% | 2140-61-6 | MFCD00006548 | 25MG
5-Methylcytidine >=99% | Purity: >=99% | Mol Wt: 257.24 | 2140-61-6 | MFCD00006548 | 25MG