Trifluridine (Trifluorothymidine) is an irreversible and orally active thymidylate synthase inhibitor that suppresses DNA synthesis. It acts as an antiviral molecule for research on HSV, rhabdovirus, and orthopoxvirus infections, and induces cell apoptosis and autophagy. Additionally, it is an anticancer agent used in studies of metastatic colorectal cancer and gastrointestinal tumors.
- Irreversible and orally active thymidylate synthase inhibitor
- Suppresses DNA synthesis
- Antiviral molecule for research on HSV, rhabdovirus, and orthopoxvirus infections
- Induces cell apoptosis and autophagy
- Acts as an anticancer agent for studies of metastatic colorectal cancer and gastrointestinal tumors