Nucleotides
Cayman Chemical N6-MethyladenosIn 1g
An adenosine analog; inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta at 10 μM; decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs at 1 mg/kg; inhibits tumor growth in the C3H/ST and C3HB/ST mouse models of spontaneous mammary adenocarcinomas; the most prevelant mRNA modification in eukaryotes and has roles in cell viability and development
Biotium Biotin-11-dCTP, 1mM in pH 7.5 TE buffer
Biotin-11-dCTP can be enzymatically incorporated into DNA via nick translation, random priming, or 3’-end terminal labeling. The number “11” is the number of atoms in the linker between biotin and dCTP. Properties: Colorless liquid; Store dessicated at -20⁰C; C28H42N7O16P3SLi4; MW: 885.4.
Trilink Bio Technologies Inc N1-Methyl-pseudouridine 5'-triphosphate
N1-Methylpseudouridine 5'-Triphosphate is a modified nucleoside triphosphate used in RNA research and synthesis. It contains a methyl group on the N1 position of the pseudouridine nucleobase. This analog is cell permeable and can be incorporated into RNA by polymerases. It is supplied as a lithium salt at ≥95% purity by TriLink BioTechnologies. The product has a molecular weight of 491.15 g/mol and is soluble up to 100 mM in water or buffer. It can be used to study RNA structure and function.
Cayman Chemical BODIPY 630650X succInImID1mg
An amine-reactive fluorescent probe; has been used, linked to adenosine A1 receptor ligands, as a fluorescent probe to quantify ligand-receptor binding; ex/em = 630/650 nm, respectively
Apexbio Technology LLC 5-Methoxy-UTP 5x100ul (100 mM)
5-Methoxy-UTP is a modified uridine triphosphate nucleotide bearing a methoxy group at the carbon-5 position This modification significantly alters the chemical properties and biological functions of the nucleotide During in vitro mRNA synthesis 5-Methoxy-UTP can be incorporated into RNA molecules generating RNAs containing 5-methoxyuridine residues Methoxy-modified RNA plays an important role in studies focusing on RNA structure function and interactions with proteins Additionally 5-Methoxy-UTP markedly improves RNA stability and protects against intracellular degradation Therefore this modification is widely utilized in gene expression research RNA drug development and gene therapy applications
Medchemexpress LLC NS-102 | 10MG
NS-102 is a selective kainate (GluK2) receptor antagonist NS-102 is a potent GluR6/7 receptor antagonist[1][2][3]
New England Biolabs, Inc. 7-deaza-dGTP – 0.3 µmol
7-deaza-dGTP (7-deaza-2-deoxyguanosine 5-triphosphate) contains a 5 mM solution of 7-deaza-dGTP as a dilithium salt. Nucleotide concentration is determined by measurements of absorbance at 257 nm. Supplied in: Milli-Q water as a lithium salt at (pH 7.0).
Selleck Chemical LLC 3 3 -cGAMP
3 3 -cGAMP (3 3 -cyclic GMP-AMP Cyclic GMP-AMP cGAMP) activates the endoplasmic reticulum (ER)-resident receptor stimulator of interferon genes (STING) thereby inducing an antiviral state and the secretion of type I IFNs
Medchemexpress LLC Cytidine-5′-triphosphate-d14 disodium | 65-47-4 | 98.0% | 541.21 | 1 MG
Cytidine-5′-triphosphate-d14 disodium | 65-47-4 | 98.0% | 541.21 | 1 MG
Medchemexpress LLC Cytidine-5'-triphosphate | 65-47-4 | 98.0% | 483.16 | 1 MG
Cytidine-5'-triphosphate | 65-47-4 | 98.0% | 483.16 | 1 MG
Medchemexpress LLC Pamidronate disodium | 57248-88-1 | 98.0% | C3H9NNa2O7P2 | 5 MG
Pamidronate disodium is a second-generation nitrogen-containing bisphosphonate that inhibits bone loss. It significantly inhibits subchondral bone loss in early osteoarthritis by upregulating osteoprotegerin expression and inhibiting RANKL, MMP-9, and TLR-4 expression in cartilage and subchondral bone, thereby alleviating cartilage degeneration. This compound also inhibits Wnt and β-catenin signaling and is suitable for research on osteoporosis and osteosarcoma.
- Inhibits bone loss.
- Upregulates osteoprotegerin expression.
- Inhibits RANKL, MMP-9, and TLR-4 expression.
- Alleviates cartilage degeneration.
- Inhibits Wnt and β-catenin signaling.
- Applicable for research on osteoporosis and osteosarcoma.
- Inhibits osteosarcoma cell viability (0.001-1000 μM, 72 h).
- Improves bone structure and alleviates cartilage degenerative changes in vivo.
Biolegend Purified anti-human CD24 Recombinant [QA21A28]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 ug
Purified anti-human CD24 Recombinant [QA21A28]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 ug
Apexbio Technology LLC N6-Methyl-ATP,10ul (100 mM)
Other sizes are also available. Please inqury us for quote.