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Nucleotides are composed of a nitrogenous base covalently bound to a 5-carbon sugar molecule and one or more phosphate functional groups. They are the molecules that make up the structural units of DNA and RNA.
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5-hme-CTP (5-hydroxymethylcytidine triphosphate) is a modified cytidine triphosphate bearing a hydroxymethyl group at the 5-position carbon This modification can enhance RNA stability and functionality During in vitro mRNA synthesis 5-hme-CTP can be incorporated into RNA molecules producing RNA containing 5-hydroxymethylcytidine Hydroxymethyl-modified RNA plays an essential role in studying RNA structure function and RNA-protein interactions Additionally 5-hme-CTP significantly improves RNA stability by reducing its intracellular degradation Thus this modified nucleotide has broad applications in gene expression research RNA-based drug development and gene therapy
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Digoxigenin-11-UTP is a modified nucleoside triphosphate used for labeling RNA probes It incorporates a digoxigenin label attached to uridine triphosphate (UTP) allowing it to be incorporated into RNA molecules during in vitro transcription reactions Digoxigenin is a non-radioactive label widely utilized in molecular biology experiments especially in situ hybridization (ISH) and Northern blotting RNA probes labeled with Digoxigenin-11-UTP exhibit high sensitivity and low background noise providing clear detection results Additionally the digoxigenin label binds specifically to anti-digoxigenin antibodies making the detection process both straightforward and highly efficient Digoxigenin-11-UTP serves as an essential tool for studying gene expression and RNA localization
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5-FAM-Alkyne is an alkyne-functionalized fluorescein derivative supplied as a solid fluorescent labeling reagent for copper-catalyzed click chemistry. It is designed for conjugation to biomolecules and use in fluorescence-based detection and imaging applications, providing reliable labeling in typical biochemical workflows.
Alkyne functional group for click chemistry.
High purity (95.0%).
Solid form, yellow to brown.
Molecular weight 413.38 g/mol.
Suitable for fluorescent labeling and imaging applications.
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