RNAi and RNA Reagents
ABclonal Technology Phospho-eIF4E-S209 Rabbit pAb
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5 end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
![ABclonal Technology [KO Validated] MEK2 Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000106115.jpg-250.jpg)
ABclonal Technology [KO Validated] MEK2 Rabbit pAb
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
Bioss KD-Validated Tripartite motif
Tripartite Motif Containing 24 Primary Antibody Unconjugated Public Immunogen Range 150-200/796 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETplus Human ME3 siRNA, Smartpool, 20 nmol
Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].
Bioss KD-Validated Pre-MRNA Processi
Pre-MRNA Splicing Tri-SnRNP Complex Factor PRPF4 Primary Antibody Unconjugated Public Immunogen Range 601-685/727 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Bioss KD-Validated Musashi RNA Bindi
Musashi RNA Binding Protein 2 Primary Antibody Unconjugated Public Immunogen Range 200-280/328 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
![ABclonal Technology [KD Validated] HDAC1 Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000135762.jpg-250.jpg)
ABclonal Technology [KD Validated] HDAC1 Rabbit pAb
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Bioss KD-Validated Glutamic-oxaloace
Glutamic-Oxaloacetic Transaminase 1 Primary Antibody Unconjugated Public Immunogen Range 150-203/203 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Meso Scale Discovery SPLEX HUM CTLA4 KitQP 25 PL
The S-PLEX Human CTLA-4 Kit by Meso Scale Diagnostics is a multiplex immunoassay kit that enables the simultaneous measurement of CTLA-4 in human serum plasma and cell culture supernatants The kit contains a 96-well plate coated with capture antibodies detection antibodies Read Buffer Diluent 2 Calibrator Blend and controls The electrochemiluminescent assay has a typical sensitivity of 0 3 pg/mL and an assay range from 0 3-2500 pg/mL The kit is for research use only and not for diagnostic procedures It allows high-throughput quantitative analysis of CTLA-4 with low sample volume requirements
Cayman Chemical THUNDRTotal CREB TRFRET C 2400
Sandwich TR-FRET immunoassay for semi-quantitative detection of Total CREB in cell lysates
Sino Biological Recombinant Mouse Integrin alpha 3 beta 1 Protein (Flag & His Tag), HPLC-verified 100 µg
A DNA sequence encoding the Mouse ITGA3 Q62470)(Phe33-Glu993) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the Mouse ITGB1 (P09055) (Gln21-Asp728) was fused with a flag tag at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the Mouse Integrin alpha 3 beta 1 Heterodimer was purified.
Bioss KD-Validated Bcl-2 Rabbit Reco
BCL2 Apoptosis Regulator Primary Antibody Unconjugated Public Immunogen Range 48-81/239 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
HORIZON DISCOVERY BIOSCIENCES LIMITED OTP HU SMG5 SIRNA 23381 SP 5NM
NC3104657 OTP HU SMG5 SIRNA 23381 SP 5NM
HORIZON DISCOVERY BIOSCIENCES LIMITED HUMAN DTL 51514 SIRNA -5 NMOL
NC3106172 HUMAN DTL 51514 SIRNA -5 NMOL
HORIZON DISCOVERY BIOSCIENCES LIMITED HUMAN HMOX1 3162 SIRNA - SET
NC3482438 HUMAN HMOX1 3162 SIRNA - SET