RNAi and RNA Reagents
Genscript Corporation FOLR1 hFc Chimera Human
Folate Receptor 1 (FOLR1) also known as Folate Receptor alpha and Folate Binding Protein (FBP) is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis the interconversion of glycine and serine and histidine breakdown FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells Has high affinity for folate and folic acid analogs at neutral pH
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETplus Non-targeting Control siRNAs #2, 5nmol
ON-TARGETplus Non-targeting Control siRNAs are the ideal negative control for RNAi experiments in human, mouse, and rat cells. ON-TARGETplus Non-targeting siRNAs were designed to leverage seed-region optimization and patented ON-TARGETplus modification patterns to have fewer off-targets than traditionally designed, unmodified negative control siRNAs. Changes in mRNA or protein levels in cells treated with these controls reflect a baseline cellular response that can be compared to the levels in cells treated with target-specific siRNA.
ABclonal Technology eIF4E Rabbit pAb
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5 end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Sigma Aldrich Fine Chemicals Biosciences SIRNA UNIV NEG CONTROL2 10NMOL
NC3732623 SIRNA UNIV NEG CONTROL2 10NMOL
BIOHIPPO h/m NRP1 shRNA Set GFP Puro
h/m NRP1 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated h/m NRP1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse neuropilin 1 (NRP1) The shRNA has been validated to meet or exceed 70% knockdown of NRP1 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Cellecta Inc Mouse Genome-Wide CRISPRi sgRNA Library, 200ug Plasmid
Mouse Genome-Wide CRISPRi sgRNA Library, 200ug Plasmid
Bioss KD-Validated Arrestin beta 1 R
Arrestin Beta 1 Primary Antibody Unconjugated Public Immunogen Range 1-48/418 Host Species Rabbit Target Species Human Mouse Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Bioss KD-Validated PCBP2 Rabbit Reco
Poly(RC) Binding Protein 2 Primary Antibody Unconjugated Public Immunogen Range 257-300/365 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
BIOHIPPO h/m FOXA1 shRNA Set GFP Puro
h/m FOXA1 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated h/m FOXA1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse forkhead box A1 (FOXA1) The shRNA has been validated to meet or exceed 70% knockdown of FOXA1 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
ABclonal Technology JAK3 Rabbit pAb
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).