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MicroRNAs (miRNAs) are small, non-coding RNA molecules found in plants, animals, and some viruses that function in RNA silencing and post-transcriptional regulation of gene expression via base-pairing with complementary sequences within mRNA molecules.
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SpCas9 mRNA expresses an optimized version of Streptococcus pyogenes protein. It can be used with a purified guideRNA sequence for genomic DNA target recognition and cleavage in the CRISPR-Cas genome editing system. Type II CRISPR-Cas system from the bacterium S. pyogenes has been adapted for genome engineering in eukaryotic systems, which requires two main components: the endoculease Cas9 and non-coding guide RNA (gRNA). The Cas9 protein can be programmed with gRNA, targeting a site-specific DNA double-strand break (DSB). Other sizes are available. Please inqury us for quote.
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hsa-miR-26b-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
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IC50: 88.41 M for hepatitis C virus Genipin, a compound derived from Gardenia jasminoides Ellis fruits, has been used over the years in traditional Chinese medicine to treat symptoms of type 2 diabetes. Other sizes are available. Please inqury us for quote.
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hsa-miR-155-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
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A critical step in mRNA processing is the addition of a 5 cap structure, a 5'-5' triphosphate linkage between the 5' initiating terminal of the RNA and a guanosine nucleotide. The cap is then methylated enzymatically at the N-7 position of the guanosine to form a mature mCAP. Other sizes are available. Please inqury us for quote.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More