Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Color
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Quantity
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136
Tocris Bioscience™ PARPYnD
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PARP inhibitor; photoaffinity probe
137
Tocris Bioscience™ MitoBrilliant Live 646
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Red fluorescent mitochondrial stain for live cells, Δψm dependent
| Target | Mitochondria Dyes and Probes |
|---|---|
| Recommended Storage | Store at -20°C |
138
Tocris Bioscience™ VH 032 amide-alkylC9-acid
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VHL ligand with alkyl linker and terminal acid for onward chemistry
139
Tocris Bioscience™ LC 2 Epimer
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Negative control for LC 2 (Cat. No. 7420)
140
Tocris Bioscience™ Pomalidomide 4'-PEG5-azide
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Cereblon ligand with PEG linker and terminal azide for onward chemistry
141
Tocris Bioscience™ Thalidomide, 5'-fluoro
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Fluoro functionalized Thalidomide; cereblon ligand for PROTACs
142
Tocris Bioscience™ Pomalidomide 5'-piperazine
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Cereblon ligand with terminal piperazine for onward chemistry
143
Tocris Bioscience™ EN6
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H+ ATPase activator; activates autophagy; inactivates mTORC1 signaling
| Target | H+-ATPase Inhibitors |
|---|---|
| CAS | 1808714-73-9 |
| Purity | 0.98 |
| Chemical Name or Material | N-[4-Fluoro-3-[(1-oxo-2-propen-1-yl)amino]phenyl]-1-(2-fluorophenyl)-1 H-pyrazole-4-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H14F2N4O2 |
144
Tocris Bioscience™ BI dihydrochloride BI hydrochloride BI hydrochloride
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DFHBI derivative for imaging of RNA in living cells that bind Broccoli aptamers
145
Tocris Bioscience™ DBCO PEG4 Biotin
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Biotinylation reagent for labeling azide-containing biomolecules via Cu(I)-free click chemistry
146
Tocris Bioscience™ Arbidol
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Inhibits replication of SARS-CoV-2 in vitro; broad spectrum antiviral
147
Tocris Bioscience™ a1A-AR Degrader 9c
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Selective α1A adrenergic receptor Degrader (PROTAC™)
148
Tocris Bioscience™ Pepstatin A Janelia Fluor 526
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Fluorogenic green-emitting lysosome tracker and stain
149
Tocris Bioscience™ Thalidomide 4'-ether-alkylC8-acid
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Cereblon ligand with alkyl linker and terminal acid for onward chemistry
150
Tocris Bioscience™ Dinaciclib
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Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| CAS | 779353-01-4 |
| Purity | 0.98 |
| Chemical Name or Material | (2 S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H28N6O2 |