Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Color
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Quantity
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151
Tocris Bioscience™ BDY FL Lenalidomide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Fluorescent cereblon ligand
152
Tocris Bioscience™ AMG 900
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent pan-Aurora kinase inhibitor
| Target | Aurora Kinase Inhibitors |
|---|---|
| CAS | 945595-80-2 |
| Purity | 98% |
| Chemical Name or Material | N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H21N7OS |
153
Tocris Bioscience™ HER2 PROTAC™ CH7C4
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective HER2 targeting PROTAC™
154
Tocris Bioscience™ Pomalidomide 5'-piperidine-acid
Cereblon ligand with piperidine linker and terminal acid for onward chemistry
155
Tocris Bioscience™ VU 0546110
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective SLO3 potassium channel inhibitor
| Target | Non-selective/Other Potassium Channel Blockers |
|---|---|
| CAS | 1421523-00-3 |
| Purity | 0.98 |
| Chemical Name or Material | 1-[4-[[(4-Methoxyphenyl)thio]methyl]-1-piperidinyl]-2-[4-[(1-methylethyl)sulfonyl]phenyl]ethanone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H31NO4S2 |
156
Tocris Bioscience™ tri-GalNAc COOH
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry
157
Tocris Bioscience™ LEI 401
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor
158
Tocris Bioscience™ OGDA
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Green fluorescent D-amino acid; compatible with STED microscopy
159
Tocris Bioscience™ TWS 119
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation
160
Tocris Bioscience™ Pomalidomide 4'-alkylC6-azide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
161
Tocris Bioscience™ CG 428-Neg
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative control for CG 428 (Cat. No. 7425)
162
Tocris Bioscience™ TH 1760
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective NUDT15 hydrolase inhibitor
| Target | Hydrolase Inhibitors |
|---|---|
| CAS | 2567914-01-4 |
| Purity | 0.95 |
| Chemical Name or Material | 6-[[4-(1 H-Indol-5-ylcarbonyl)-1-piperazinyl]sulfonyl]-2(3 H)-benzoxazolone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H18N4O5S |
163
Tocris Bioscience™ INT 131
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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PPARγ partial agonist
| Target | PPAR gamma/NR1C3 |
|---|---|
| CAS | 315224-26-1 |
| Purity | 0.98 |
| Chemical Name or Material | 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H12Cl4N2O3S |
164
Tocris Bioscience™ SGC CK2-1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2
| Target | Casein Kinase 2 Inhibitors |
|---|---|
| CAS | 2470424-39-4 |
| Purity | 0.98 |
| Chemical Name or Material | N-[5-[[3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]propanamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H21N7O |
165
Tocris Bioscience™ Pomalidomide 4'-alkylC4-azide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry