Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ Polybrene
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Viral transduction enhancer
Tocris Bioscience™ Imipramine hydrochloride
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Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment
Tocris Bioscience™ Calcitriol
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CAS: 32222-06-3 Molecular Formula: C27H44O3
| CAS | 32222-06-3 |
|---|---|
| Molecular Formula | C27H44O3 |
Tocris Bioscience™ L-741,742 hydrochloride
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CAS: 874882-93-6 Molecular Formula: C23H26Cl2N2O
| CAS | 874882-93-6 |
|---|---|
| Molecular Formula | C23H26Cl2N2O |
Tocris Bioscience™ Doxazosin mesylate
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CAS: 77883-43-3 Molecular Formula: C24H29N5O8S
| CAS | 77883-43-3 |
|---|---|
| Molecular Formula | C24H29N5O8S |
Tocris Bioscience™ BAPTA AM
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CAS: 126150-97-8 Molecular Formula: C34H40N2O18
| CAS | 126150-97-8 |
|---|---|
| Molecular Formula | C34H40N2O18 |
Tocris Bioscience™ Acifran
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CAS: 72420-38-3 Molecular Formula: C12H10O4
| CAS | 72420-38-3 |
|---|---|
| Molecular Formula | C12H10O4 |
Tocris Bioscience™ Brequinar sodium
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Potent and selective DHODH inhibitor.
| Target | DHODH Inhibitors |
|---|---|
| CAS | 96201-88-6 |
| Chemical Name or Material | 6-Fluoro-2-(2′-fluoro[1,1′-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C23H14F2NO2Na |
| Formula Weight | Observed MW: 397.35 |
| Assay Percent Range | >99% |
Tocris Bioscience™ Filipin III
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Polyene antibiotic; inhibits formation of pathological isoform of prion protein
Tocris Bioscience™ NMS 873
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Potent and selective p97 ATPase (VCP) allosteric inhibitor
| CAS | 1418013-75-8 |
|---|---|
| Chemical Name or Material | 3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]pyridine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C27H28N4O3S2 |
| Formula Weight | Observed MW: 520.67 |
| Assay Percent Range | >98% |
Tocris Bioscience™ ci-IP3/PM
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Caged inositol triphosphate
Tocris Bioscience™ Pimonidazole
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Hypoxia detection reagent
| CAS | 70132-50-2 |
|---|---|
| Chemical Name or Material | α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C11H18N4O3 |
| Formula Weight | Observed MW: 254.29 |
| Assay Percent Range | >98% |
Tocris Bioscience™ SB 239063
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CAS: 193551-21-2 Molecular Formula: C20H21FN4O2
| CAS | 193551-21-2 |
|---|---|
| Molecular Formula | C20H21FN4O2 |
Tocris Bioscience™ GSK2578215A
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Potent, selective LRRK2 inhibitor; brain penetrant
| CAS | 1285515-21-0 |
|---|---|
| Chemical Name or Material | 5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C24H18FN3O2 |
| Formula Weight | Observed MW: 399.42 |
| Assay Percent Range | >99% |
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Tocris Bioscience™ Nor NOHA monoacetate
Tocris Bioscience™ Nor NOHA monoacetate
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Arginase inhibitor