Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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181
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181
Tocris Bioscience™ TM 38837
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent CB1 inverse agonist; peripherally restricted
182
Tocris Bioscience™ RU.521
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Potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS)
| Target | Synthase/Synthetase Inhibitors |
|---|---|
| CAS | 2262452-06-0 |
| Purity | 0.98 |
| Chemical Name or Material | 3-[1-(6,7-Dichloro-1 H-benzimidazol-2-yl)-5-hydroxy-3-methyl-1 H-pyrazol-4-yl]-1(3 H)-isobenzofuranone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H12Cl2N4O3 |
183
Tocris Bioscience™ Pomalidomide 4'-alkylC2-azide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
184
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Pleconaril, Thermo Scientific™
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Pleconaril, Thermo Scientific™
CAS: 153168-05-9 Molecular Formula: C18 H18 F3 N3 O3 Molecular Weight (g/mol): 381.36 MDL Number: MFCD00923611 InChI Key: KQOXLKOJHVFTRN-UHFFFAOYSA-N IUPAC Name: 3-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole SMILES: CC1=NOC(CCCOC2=C(C)C=C(C=C2C)C2=NOC(=N2)C(F)(F)F)=C1
| CAS | 153168-05-9 |
|---|---|
| Molecular Weight (g/mol) | 381.36 |
| MDL Number | MFCD00923611 |
| SMILES | CC1=NOC(CCCOC2=C(C)C=C(C=C2C)C2=NOC(=N2)C(F)(F)F)=C1 |
| IUPAC Name | 3-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole |
| InChI Key | KQOXLKOJHVFTRN-UHFFFAOYSA-N |
| Molecular Formula | C18 H18 F3 N3 O3 |
185
R&D Systems™ Cy5 Labeled Heparan Sulfate Proteoglycan (Cy5-HSPG)
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Used as a substrate to study activity of various heparanases and heparinases and protein heparan sulfate interactions
187
Tocris Bioscience™ JNJ 39758979 Dihydrochloride
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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High affinity and selective histamine H4 antagonist; orally bioavailable
| Purity | 98% |
|---|---|
| Chemical Name or Material | 4-[(3R)-3-Amino-1-pyrrolidinyl]-6-(1-methylethyl)-2-pyridinamine dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C11H19N5.2HCl |
| Formula Weight | 294.22 |
188
189
Valaciclovir hydrochloride hydrate, Thermo Scientific Chemicals
CAS: 124832-27-5 Molecular Formula: C13H21ClN6O4
| CAS | 124832-27-5 |
|---|---|
| Molecular Formula | C13H21ClN6O4 |
192
Tocris Bioscience™ VH 032 amide-alkylC6-amine
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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VH 032-AlkylC6-Amine
193
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Thermo Scientific Chemicals Urapidil hydrochloride
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Thermo Scientific Chemicals Urapidil hydrochloride
CAS: 64887-14-5 Molecular Formula: C20H29N5O3·HCl
| CAS | 64887-14-5 |
|---|---|
| Molecular Formula | C20H29N5O3·HCl |
194
| CAS | 65195-55-3 |
|---|---|
| Health Hazard 3 | GHS09: Environment |
| Color | White to Light-yellow |
| Health Hazard 2 | GHS08: Health hazard |
| Physical Form | Crystalline Powder |
| Health Hazard 1 | GHS06: Skull and crossbones |
| Chemical Name or Material | Avermectin |
| Recommended Storage | Refrigerator +4°C |
| Molecular Formula | C48 H72 O14 |
| EINECS Number | 265-610-3 |
| Formula Weight | 873.09 |
195
| CAS | 123524-52-7 |
|---|---|
| Molecular Formula | C33H34N4O6 |