Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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196
Tocris Bioscience™ DBCO-NHS
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Amine reactive and azide reactive building block
197
Tocris Bioscience™ Pomalidomide 4'-PEG5-azide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Cereblon ligand with PEG linker and terminal azide for onward chemistry
198
Tocris Bioscience™ GLPG 0187
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent αv integrin inhibitor
| Target | Integrin Receptor Inhibitors |
|---|---|
| CAS | 1320346-97-1 |
| Purity | 0.97 |
| Chemical Name or Material | 3-[[2,5-Dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-L-alanine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C29H37N7O5S |
199
Tocris Bioscience™ R 547
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and selective cdk inhibitor
200
Tocris Bioscience™ VH 032 amide-PEG1-amine
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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VH 032-PEG1-amine
201
Tocris Bioscience™ MK 2206 dihydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective allosteric Akt1, Akt2 and Akt3 inhibitor
| Target | Akt (Protein Kinase B) Inhibitors |
|---|---|
| CAS | 1032350-13-2 |
| Purity | 0.98 |
| Chemical Name or Material | 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H21N5O.2HCl |
202
Tocris Bioscience™ THAL SNS 032
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and selective Cdk9 Degrader (PROTAC™)
203
Tocris Bioscience™ Tazemetostat
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and selective EZH2 inhibitor
| Target | EZH2 Inhibitor |
|---|---|
| CAS | 1403254-99-8 |
| Purity | 0.97 |
| Chemical Name or Material | N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-4-methyl-4'-(4-morpholinylmethyl)[1,1'-biphenyl]-3-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C34H44N4O4 |
204
Tocris Bioscience™ KT 182
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent, selective and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor
207
Tocris Bioscience™ BAY 805
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and selective inhibitor of USP21; also NF-κB activator
| Target | Deubiquitinating Enzyme Inhibitors |
|---|---|
| CAS | 2925481-88-3 |
| Purity | 0.98 |
| Chemical Name or Material | N-[(1R)-1-[[[5-[(4-Cyanophenyl)methyl]-1,3,4-thiadiazol-2-yl]amino]carbonyl]-3-methylbutyl]-1-(trifluoromethyl)cyclohexanecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H28F3N5O2S |
210
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Thermo Scientific Chemicals Tiotropium bromide
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Thermo Scientific Chemicals Tiotropium bromide
CAS: 139404-48-1 Molecular Formula: C19H22BrNO4S2
| CAS | 139404-48-1 |
|---|---|
| Molecular Formula | C19H22BrNO4S2 |