Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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2,206
Tocris Bioscience™ Losartan potassium
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CAS: 124750-99-8 Molecular Formula: C22H25ClKN6O
| CAS | 124750-99-8 |
|---|---|
| Molecular Formula | C22H25ClKN6O |
2,207
Tocris Bioscience™ DOTAP
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Cationic agent for liposome and LNP formation
2,208
Tocris Bioscience™ A 485
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Histone Acetyltransferase Inhibitors
| CAS | 1889279-16-6 |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Synonym | (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2′,4′-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5′-oxazolidine]-3′-acetamide |
| Molecular Formula | C25H24F4N4O5 |
| Formula Weight | 536.48 |
2,209
Tocris Bioscience™ ML 133 hydrochloride
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CAS: 1222781-70-5 Molecular Formula: C19H20ClNO
| CAS | 1222781-70-5 |
|---|---|
| Molecular Formula | C19H20ClNO |
2,210
Tocris Bioscience™ PH 797804
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Potent and selective p38α/β inhibitor
| Target | p38 Inhibitors |
|---|---|
| CAS | 1358027-80-1 |
| Purity | >98% |
| Chemical Name or Material | (-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H19BrF2N2O3 |
| Formula Weight | 477.3 |
2,211
Tocris Bioscience™ RS 246204
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R-Spondin-1 substitute used to initiate small intestinal organoids
| Target | Compounds for Stem Cell Proliferation & Renewal |
|---|---|
| Recommended Storage | Store at -20°C |
2,212
Tocris Bioscience™ 4-P-PDOT
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CAS: 134865-74-0 Molecular Formula: C19H21NO
| CAS | 134865-74-0 |
|---|---|
| Molecular Formula | C19H21NO |
2,213
Tocris Bioscience™ CP 122721 hydrochloride
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High affinity NK1 receptor antagonist
| CAS | 145877-52-7 |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Synonym | (2S,3S)-N-[[2-Methoxy-5-(trifluoromethoxy)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride |
| Molecular Formula | C20H23F3N2O2.2HCl |
| Formula Weight | 453.33 |
2,214
Tocris Bioscience™ PF 04628935
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Potent ghrelin receptor inverse agonist
| CAS | 1383719-97-8 |
|---|---|
| Chemical Name or Material | 1-[2-[[2-Chloro-4-(2H-1,2,3-triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H26ClN7OS |
| Formula Weight | Observed MW: 496.03 |
| Assay Percent Range | >98% |
2,215
Tocris Bioscience™ PD 98059
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MEK inhibitor
| Inhibitors | PD 98059 |
|---|---|
| CAS | 167869-21-8 |
| Product Type | PD 98059 |
| Molecular Weight (g/mol) | M.W. (Observed): 267.28 |
| Purity | 98% |
| Recommended Storage | Room Temperature |
| Molecular Formula | 2-(2-Amino-3-methoxyphenyl)-4 H-1-benzopyran-4-one |
2,216
Tocris Bioscience™ Everolimus
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mTOR inhibitor;immunosuppressant
2,217
Tocris Bioscience™ GM 6001
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CAS: 142880-36-2 Molecular Formula: C20H28N4O4
| CAS | 142880-36-2 |
|---|---|
| Molecular Formula | C20H28N4O4 |
2,218
Tocris Bioscience™ iFSP1
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Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer
| Target | Other Reductase Inhibitors |
|---|---|
| CAS | 150651-39-1 |
| Purity | 98% |
| Chemical Name or Material | 1-Amino-3-(4-methylphenyl)-pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H13N5 |
2,219
Tocris Bioscience™ Probenecid
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CAS: 57-66-9 Molecular Formula: C13H19NO4S
| CAS | 57-66-9 |
|---|---|
| Molecular Formula | C13H19NO4S |
2,220
Tocris Bioscience™ Withaferin A
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Inhibits NF-κB activation