Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Quantity
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2,221
Tocris Bioscience™ AC 265347
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CaSR biased allosteric modulator
| CAS | 1253901-26-6 |
|---|---|
| Chemical Name or Material | α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C17H17NOS |
| Formula Weight | Observed MW: 283.39 |
| Assay Percent Range | >99% |
2,222
Tocris Bioscience™ CSN5i-3
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Potent and selective CSN5 (COP9 signalosome) inhibitor
2,223
Tocris Bioscience™ JTE 013
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S1P2 receptor antagonist
2,224
Tocris Bioscience™ ML 418
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Kir 7.1 inhibitor. Also inhibits Kir 6.2
| CAS | 1928763-08-9 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | Isopropyl (1-((5-chloro-8-hydroxyquinolin-7-yl)methyl)piperidin-4-yl)carbamate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H24CIN3O3 |
2,225
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Tocris Bioscience™ DPTIP
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Tocris Bioscience™ DPTIP
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Potent and selective N-SMase2 inhibitor; brain penetrant
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H18N2O3S |
| Formula Weight | 378.45 |
2,226
Tocris Bioscience™ CHIR 99021
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
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CAS: 252917-06-9 Molecular Formula: C22H18Cl2N8
| CAS | 252917-06-9 |
|---|---|
| Molecular Formula | C22H18Cl2N8 |
2,227
Tocris Bioscience™ Nefiracetam
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CAS: 77191-36-7 Molecular Formula: C14H18N2O2
| CAS | 77191-36-7 |
|---|---|
| Molecular Formula | C14H18N2O2 |
2,228
Tocris Bioscience™ TASP 0277308
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Potent and selective S1P1 receptor antagonist; inhibits angiogenesis
2,229
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Tocris Bioscience™ 680C91
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Tocris Bioscience™ 680C91
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective tryptophan 2,3-dioxygenase (TDO) inhibitor
| CAS | 163239-22-3 |
|---|---|
| Chemical Name or Material | 6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C15H11FN2 |
| Formula Weight | Observed MW: 238.26 |
| Assay Percent Range | >98% |
2,230
Tocris Bioscience™ MD13
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Potent MIF Degrader (PROTAC™)
2,231
Tocris Bioscience™ 1A-116
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Rac1 inhibitor; blocks Rac1-P-Rex1 interaction
| CAS | 1430208-73-3 |
|---|---|
| Product Type | Inhibitor |
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H16F3N3 |
| Formula Weight | 307.31 |
2,232
Tocris Bioscience™ PP 1
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CAS: 172889-26-8 Molecular Formula: C16H19N5
| CAS | 172889-26-8 |
|---|---|
| Molecular Formula | C16H19N5 |
2,233
Tocris Bioscience™ PF 04457845
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Potent and selective irreversible FAAH inhibitor
| CAS | 1020315-31-4 |
|---|---|
| Chemical Name or Material | N-3-Pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C23H20F3N5O2 |
| Formula Weight | Observed MW: 455.43 |
| Assay Percent Range | >98% |
2,234
Tocris Bioscience™ Pladienolide B
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mRNA splicing inhibitor; antitumor
2,235
Tocris Bioscience™ VH 032 amide-PEG4-acid
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VHL ligand with PEG linker and terminal acid for onward chemistry