Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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2,716
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2,716
Tocris Bioscience™ BSJ-04-132
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Selective Cdk4 degrader
2,717
Tocris Bioscience™ CID 755673
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CAS: 521937-07-5 Molecular Formula: C12H11NO3
| CAS | 521937-07-5 |
|---|---|
| Molecular Formula | C12H11NO3 |
2,718
Tocris Bioscience™ Src I1
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Dual site Src kinase inhibitor
| Inhibitors | Src I1 |
|---|---|
| Product Type | Src I1 |
| Molecular Weight (g/mol) | 373.4 |
| Purity | >99% |
2,719
Tocris Bioscience™ STO-609 acetate
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Selective CaM kinase kinase inhibitor
| CAS | 1173022-21-3 |
|---|---|
| Solubility | Soluble to 10mM with sonication in DMSO |
| Chemical Name or Material | 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C19H10N2O3.C2H4O2 |
| Formula Weight | Observed MW: 374.35 |
| Assay Percent Range | >98% |
2,720
Tocris Bioscience™ PD 166793
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CAS: 199850-67-4 Molecular Formula: C17H18BrNO4S
| CAS | 199850-67-4 |
|---|---|
| Molecular Formula | C17H18BrNO4S |
2,721
Tocris Bioscience™ TC-MCH 7c
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CAS: 864756-35-4 Molecular Formula: C24H25FN2O3
| CAS | 864756-35-4 |
|---|---|
| Molecular Formula | C24H25FN2O3 |
2,722
Tocris Bioscience™ EED 226
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Potent and selective EED inhibitor
| Target | EED |
|---|---|
| CAS | 2083627-02-3 |
| Chemical Name or Material | N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine |
| Recommended Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
| Molecular Formula | C17H15N5O3S |
2,723
Tocris Bioscience™ CW 008
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PKA signaling activator; promotes osteogenesis from hMSCs
| Target | Protein Kinase A Activators |
|---|---|
| CAS | 1134613-19-6 |
| Purity | >98% |
| Chemical Name or Material | 4-Fluoro-N-[5-fluoro-6-(5-methoxypyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]benzamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C21H14F2N6O2 |
| Formula Weight | 420.37 |
2,724
Tocris Bioscience™ SB 206553 hydrochloride
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CAS: 1197334-04-5 Molecular Formula: C17H17ClN4O
| CAS | 1197334-04-5 |
|---|---|
| Molecular Formula | C17H17ClN4O |
2,725
Tocris Bioscience™ dBRD9
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Potent and selective BRD9 Degrader (PROTAC™)
2,726
Tocris Bioscience™ AZ 1729
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FFA2 allosteric agonist; displays bias for the Gi signaling pathway
2,727
Tocris Bioscience™ RITA
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CAS: 213261-59-7 Molecular Formula: C14H12O3S2
| CAS | 213261-59-7 |
|---|---|
| Molecular Formula | C14H12O3S2 |
2,728
Tocris Bioscience™ TG 003
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CAS: 719277-26-6 Molecular Formula: C13H15NO2S
| CAS | 719277-26-6 |
|---|---|
| Molecular Formula | C13H15NO2S |
2,729
Tocris Bioscience™ NH 125
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CAS: 278603-08-0 Molecular Formula: C27H45IN2
| CAS | 278603-08-0 |
|---|---|
| Molecular Formula | C27H45IN2 |
2,730
Tocris Bioscience™ Trametinib
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Potent and selective MEK inhibitor; orally bioavailable
| Target | MEK Inhibitors |
|---|---|
| CAS | 871700-17-3 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H23FIN5O4 |