Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC BAFFR/TNFRSF13C HUM 20UG
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5000187473 BAFFR/TNFRSF13C HUM 20UG
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Medchemexpress LLC BCMA/TNFRSF17 HUMAN 50UG
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5000187474 BCMA/TNFRSF17 HUMAN 50UG
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Medchemexpress LLC 4-1BBL/TNFSF9 TRIMER 50UG
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5000187475 4-1BBL/TNFSF9 TRIMER 50UG
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Medchemexpress LLC DELTA-LIKE 3/DLL3 H 100UG
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5000187551 DELTA-LIKE 3/DLL3 H 100UG
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Medchemexpress LLC CD3 EPSILON 1-27 PEP 100UG
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5000187556 CD3 EPSILON 1-27 PEP 100UG
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Medchemexpress LLC FIBRILLIN-1/ASPROSIN 100UG
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5000187559 FIBRILLIN-1/ASPROSIN 100UG
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Medchemexpress LLC WISP1/CCN4 MOUSE H 10UG
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5000187560 WISP1/CCN4 MOUSE H 10UG
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Medchemexpress LLC THSD7A HUMAN HEK29 100UG
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5000187564 THSD7A HUMAN HEK29 100UG
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Medchemexpress LLC Act-660602 | 1646267-59-5 | C20H20F6N8OS | 100 MG
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ACT-660602 is an orally active antagonist of chemokine receptor (CXCR3) with an IC50 value of 204 nM. It inhibits T-cell migration and has shown efficacy in an acute lung injury model. This compound can be used for autoimmune diseases research.
- Orally active antagonist of chemokine receptor (CXCR3)
- Inhibits T-cell migration
- Demonstrates efficacy in an acute lung injury model
- Suitable for autoimmune diseases research
- Exhibits selectivity for CXCR3 over hERG (IC50 18 μM)
- Displays non-competitive binding to CXCL10 and CXCL11
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AdipoGen Ponasterone A (25 mg)
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Chemical. CAS: 13408-56-5. Formula: C27H44O6. MW: 464.6. Semi-synthetic. A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. Analog of ecdysone with similar properties to muristerone A. Functional, reliable and economical substitute for muristerone A as an inducer for the ecdysone-inducible mammalian expression system. Induces expression of beta-galactosidase to levels similar to those obtained with muristerone A induction. Potent compound for ecdysteroid activity. Insect steroid hormone involved in regulating metamorphosis.
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Cayman Chemical ANTIBODY VorucIclIb 1mg
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A pan-CDK inhibitor (Kis = 0.626-9.1 nM); selective for CDKs over MAK and ICK (Kis = 259 and 481 nM, respectively), in a panel of 48 kinases; decreases Mcl-1 levels and increased cleaved PARP levels in six DLBCL cell lines at 0.5-5 µM; reduces tumor growth by 56.3% in a Ri-1 mouse xenograft model at 200 mg/kg
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Cayman Chemical MDMB4enPICA butnoIc acId m 5mg
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An analytical reference standard that is structurally similar to known synthetic cannabinoids; a potential metabolite of MDMB-4en-PICA based on the published metabolism of MDMB-PICA; intended for research and forensic applications
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Cayman Chemical SynthetIc ArtemItIn 5mg
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A flavonoid with diverse biological activities; scavenges peroxyl radicals in a cell-free assay; inhibits 5-LO (IC50 = 54.6 µM); active against P. falciparum (IC50 = 26 µM); cytotoxic to HL-60 leukemia cells (IC50 = 30.98 µM); decreases mean arterial blood pressure in normotensive rats, as well as reduces angiotensin I-induced, but not angiotensin II-induced, increases in mean arterial blood pressure in rats, at 0.75 mg/kg
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Echelon Biosciences Research Labs SHIP2 ENZYME 100 ug
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This His-tagged, recombinant human SHIP2 (truncated form containing SH2 domain and inositol 5-phophatase catalytic domain) is tested for activity against PIP3 and is purified from E.coli using Ni-NTA column chromatography. SH2-containing 5`-inositol phosphatase 2 (SHIP2) is a lipid phosphatase which converts PI(3,4,5)P3 to PI(3,4)P2 in the negative regulation of insulin signaling with the fundamental impact on the state of insulin resistance. SHIP2 down-regulates insulin signaling and is present at higher levels in diabetes and obesity. Abnormalities in SHIP function are increasingly linked to disease, in particular in the role of SHIP as a negative regulator of cytokine and immune receptor signalling. This item is non returnable
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Cayman Chemical ANTIBODY GSK1070916 10mg
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A potent inhibitor of Aurora B and C (Kis = 0.38 and 1.5 nM, respectively); >250-fold selective for Aurora B and C over Aurora A; inhibits proliferation of A549 lung cancer cells in vitro (EC50 = 7 nM); inhibits proliferation in a panel of 100 tumor cell lines (EC50s = <10 nM); inhibits histone H3 phosphorylation in a COLO 205 mouse xenograft model and induces tumor regression in an HL-60 mouse xenograft model; reduces tumor growth in 10 mouse xenograft models
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