Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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121
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135
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60,533
results
121
R&D Systems™ Sonidegib
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent Smoothened receptor antagonist
| Target | Smoothened |
|---|---|
| CAS | 956697-53-3 |
| Molecular Formula | C26H26F3N3O3 |
122
123
| CAS | 81938-43-4 |
|---|---|
| Molecular Formula | 0·5 Ca |
124
R&D Systems™ VH 032, thiol
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Functionalized VHL ligand for PROTAC™; development
125
R&D Systems™ AS 99
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective ASH1L histone methyltransferase inhibitor
126
R&D Systems™ CX08005
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Competitive PTP1B inhibitor
| CAS | 1256341-22-6 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H39N04 |
127
R&D Systems™ 5-InoAz
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Metabolic probe for labeling mycobacterium cell envelope
| Target | Glycobiology Probes |
|---|---|
| CAS | 1218932-97-8 |
| Purity | 0.9 |
| Chemical Name or Material | 5-Azido-5-deoxy-myo-inositol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C6H11N3O5 |
128
R&D Systems™ GSK 2239633A
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent CCR4 antagonist
| CAS | 1240516-71-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[[3-[[3-[[(5-Chloro-2-thienyl)sulfonyl]amino]-4-methoxy-1H-indazol-1-yl]methyl]phenyl]methyl]-2-hydroxy-2-methylpropanamide |
| Molecular Formula | C24H25ClN4O5S2 |
129
R&D Systems™ E 7820
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. α2 integrin inhibitor; anti-angiogenic
| Target | Integrin Receptor Inhibitors |
|---|---|
| CAS | 289483-69-8 |
| Purity | 98% |
| Chemical Name or Material | 3-Cyano-N-(3-cyano-4-methyl-1 H-indol-7-yl)benzenesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H12N4O2S |
| Formula Weight | 336.37 |
130
R&D Systems™ H 151
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. STING antagonist
| Target | STING Antagonists |
|---|---|
| CAS | 941987-60-6 |
| Purity | 98% |
| Chemical Name or Material | N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea |
| Recommended Storage | Store at 4°C |
| Synonym | ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173 |
| Molecular Formula | C17H17N3O |
| Formula Weight | 279.34 |
131
R&D Systems™ TRAM 1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Chemical inducer of proximity for dTAG protein FKBPF36V and ecDHFR tags
132
R&D Systems™ Sitagliptin Phosphate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective DPP IV (DPP4) inhibitor (IC50 = 18 nM)
| CAS | 654671-78-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (3R)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone phosphate |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C16H15F6N5O.H3O4P |
| Formula Weight | 505.31 |
133
R&D Systems™ CU-76
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective inhibitor of cyclic GMP-AMP synthase (cGAS)
135
R&D Systems™ 4-Octyl Itaconate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Nrf2 activator; cell permeable
| CAS | 3133-16-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-Methylenebutanedioic acid 4-octyl ester |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C13H22O4 |
| Formula Weight | 242.31 |