Crosslinking Reagents
Diagenode Inc ChIP Cross-link Gold, 250x concentrated solution, 600 μL
The Diagenode ChIP Cross-link Gold (C01019027) is a specialized reagent that enhances chromatin immunoprecipitation (ChIP) assays by stabilizing protein-protein interactions. This innovative product addresses the limitations of traditional formaldehyde fixation, particularly for proteins not directly bound to DNA. It facilitates a sequential fixation protocol that stabilizes protein complexes before interlinking protein-DNA, yielding a more comprehensive view of chromatin architecture.
- Application in chromatin immunoprecipitation (ChIP)
- Enhances protein-protein cross-linking
- Targets higher-order and dynamic protein interactions
- Shipped at -20°C
- Store at -20°C; for long term, store at -80°C
- Volume of 600 μL
- Avoid multiple freeze-thaw cycles
- 250x concentrated solution
Bioworld DSP, 1 g
DSP, Dithiobis(succinimidyl propionate)Primary amine reactiveThiol cleavableReferences: 1.) Lomant, A.J. and Fairbanks, G. (1976) J. Mol. Biol. 104, 243-261. 2.) Tavers, R.C., et al. (1982) J. Biol. Chem. 257, 10708-10714.M.W. = 404.4
Vector Laboratories Sulfo S-HyNic Linker, 10 mg S-1002-010
Sulfo S-HyNic Linker (Water Soluble), 10 mg. S-HyNic heterobifunctional crosslinker is fundamental to SoluLINK bioconjugation technology. Sulfo-S-HyNic reacts with primary amines on proteins (through lysine amino acids) or amino-modified oligonucleotides or surfaces, introducing a HyNic linker that forms stable covalent conjugates with biomolecules possessing 4FB linkers. Sulfo-S-HyNic contains a Sulfo-NHS ester, which makes this linker water soluble. No DMF or other organic solvents are necessary to dissolve the linker prior to use.
Medchemexpress LLC Sulfo-EGS 5mg | 167410-92-6 | 616.48 g/mol | C18H20N2O18S2 | 5 MG
Sulfo-EGS (ethylene glycol bis(sulfosuccinimidyl succinate)) is a water-soluble, homobifunctional, amine-reactive crosslinker used in biochemical research to covalently link proximal amine-containing residues and probe protein-protein or protein-peptide interactions. It is commonly used to map spatial relationships within protein complexes and to stabilize transient interactions for analysis.
- Water-soluble crosslinker suitable for aqueous reactions.
- Homobifunctional and targets primary amines.
- Enables mapping of spatial proximity in protein complexes.
- Supplied at research-scale quantity for laboratory use.
- Typical purity approximately 90% as supplied.
Medchemexpress LLC Pentanedioic acid, 1,5-bis(2,5-dioxo-1-pyrrolidinyl) ester | 79642-50-5 | ≥98.0% | 326.26 | 25 MG
DSG Crosslinker is an amine-reactive and noncleavable protein crosslinker. It enables stable protein-protein, peptide, and biomolecule conjugation.
- Amine-reactive and noncleavable protein crosslinker.
- Enables stable protein-protein, peptide, and biomolecule conjugation.
Cayman Chemical GlycohyodeoxycholIc AcId 50mg
A major metabolite of hyodeoxycholic acid in humans; supplementation in prairie dogs fed a lithogenic diet decreases the frequency of cholesterol crystals in the gallbladder; inhibits the activity of cholesterol 7α-hydroxylase
Medchemexpress LLC 1,2-distearoyl-rac-glycero-3-methylpolyoxyethylene | 308805-39-2 | 100.0% | 2000 (average) | C42H82O6 | 25 MG
DSG-PEG (MW 2000) is a methoxy-terminated PEGylated lipid used to incorporate polyethylene glycol chains into lipid bilayers. It is commonly used in liposome and lipid nanoparticle formulations to provide steric stabilization and extend circulation time. The material is supplied as a solid suitable for laboratory formulation and storage.
- Average molecular weight 2000 for PEG chain
- High purity (99.97%) suitable for formulation work
- Provides steric stabilization when incorporated into liposomes
- White to off-white solid, convenient powder form
- Recommended storage: powder at -20°C (long term) or 4°C (short term)