Protein Modification Reagents
Medchemexpress LLC Cholesterol-PEG 600 | 69068-97-9 | 1,055.60 g/mol | C68H110O8 | 1 G
Cholesterol-PEG 600 is a cholesterol-terminated polyethylene glycol reagent (average PEG MW ~600) used in life-science research to modify lipid assemblies and improve amphiphilic conjugation. It is supplied as an oil (off-white to light yellow) for formulation into liposomes, nanoparticles, and other delivery systems. For research use only.
![Medchemexpress LLC Propanoic acid, 3-[2-[2-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]ethoxy]ethoxy]- | 581065-93-2 | 97.8% | 391.50 g·mol⁻¹ | C16H25NO6S2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202398.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]ethoxy]ethoxy]- | 581065-93-2 | 97.8% | 391.50 g·mol⁻¹ | C16H25NO6S2 | 100 MG
(2-pyridyldithio)-PEG4 acid is a cleavable PEG linker containing four ethylene glycol units and a 2-pyridyldithio terminal group, used to attach payloads to antibodies via disulfide chemistry for antibody-drug conjugate (ADC) synthesis and other bioconjugation applications.
- Cleavable disulfide-based linker for controlled payload release.
- Four-unit PEG spacer provides flexibility and solubility.
- 2-pyridyldithio group enables facile thiol-based conjugation.
- Suitable for ADC synthesis and general bioconjugation workflows.
- Supplied as a solid and commonly available in a 100 mg pack size.
Medchemexpress LLC Propargyl-PEG4-NHS ester | 1428629-70-2 | 97.0% | 357.36 | C16H23NO8 | 1 G
Propargyl-PEG4-NHS ester is an NHS-activated 4-unit polyethylene glycol (PEG) linker bearing a terminal propargyl (alkyne) group used for bioconjugation and click chemistry. It reacts with amine-containing molecules via the NHS ester and enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for linker installation in antibody-drug conjugates and other bioconjugation workflows. Supplied as a viscous liquid for research use.
- 4-unit PEG linker with terminal alkyne functional group.
- NHS ester provides amine-reactive conjugation chemistry.
- Compatible with copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- High purity (97.0%) suitable for research applications.
- Soluble in DMSO (≈200 mg/mL) and common co-solvent mixtures for in vivo dosing.
- Available in multiple pack sizes, including 1 g.
Medchemexpress LLC Dopamine-PEG-N3 MW 25mg
Dopamine-PEG-N3 (MW 2000) (Dopamine-PEG-Azide (MW 2000)) is a compound composed of dopamine PEG segments and an azide group (-N3) Dopamine-PEG-N3 (MW 2000) can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials Dopamine-PEG-N3 (MW 2000) is a click chemistry reagent It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group
Cayman Chemical dPE-PEG 2000-CoH 10mg
A PEGylated derivative of DSPE; has been used to link transferrin receptors to the surface of liposomes encapsulating doxorubicin for targeted delivery of doxorubicin in vitro and in vivo; nanomicelles containing DSPE-PEG(2000)-COOH linked to borneol and encapsulating doxorubicin reduce tumor growth and metastasis in an in situ C6 murine model of glioblastoma
eMolecules Broadpharm / m-PEG3-S-PEG1-t-butyl ester / 250mg / 303671220 / BP-23152 / 98.000 / 2365419-97-0 / MFCD29764331 / 352.490 / C16H32O6S
Broadpharm / m-PEG3-S-PEG1-t-butyl ester / 250mg / 303671220 / BP-23152 / 98.000 / 2365419-97-0 / MFCD29764331 / 352.490 / C16H32O6S
Medchemexpress LLC m-PEG-DMG | 5,000 Da (average) | 10 MG
m-PEG-DMG (MW 5000) is a methoxy-terminated polyethylene glycol (PEG) conjugated to a dimyristoyl glycerol (DMG) lipid tail used as a PEG-lipid component in lipid nanoparticle and drug delivery formulations. It provides steric stabilization and can improve the delivery efficiency and tissue specificity of poorly soluble drugs.
- Used as a PEG-lipid in lipid nanoparticles and drug delivery research.
- Average molecular weight about 5,000 Da.
- Typically supplied as a powder with recommended storage: powder -20°C; in solvent -80°C for 6 months or -20°C for 1 month.
- Solubility in DMSO approximately 50 mg/mL (ultrasonic assistance may be required).
- Provides steric stabilization to nanoparticle surfaces and can reduce aggregation and opsonization.
Medchemexpress LLC (S,R,S)-Ahpc-peg2-n3 | 2010159-45-0 | 99.9% | 601.72 g/mol | C28H39N7O6S | 10 MG
(S,R,S)-AHPC-PEG2-N3 is a VHL E3 ligase ligand-linker conjugate that incorporates an (S,R,S)-AHPC-based VHL ligand linked to a two-unit PEG spacer terminating in an azide group. It is supplied as a research reagent for use in PROTAC development and for click-chemistry conjugation.
- VHL E3 ligase ligand-linker conjugate.
- Azide terminal group for click chemistry conjugation.
- Two-unit PEG spacer provides a flexible linker.
- Molecular weight 601.72 g/mol.
- Soluble in DMSO (125 mg/mL) and ethanol (50 mg/mL); ultrasonic assistance recommended.
- Store at -20°C under nitrogen; in solvent, store at -80°C (6 months) or -20°C (1 month).