Protein Modification Reagents
eMolecules 1924596-31-5 | Mal-amido-PEG8-TFP ester | Broadpharm | MFCD28505514 | 740.699 | C32H44F4N2O13 | 98.000 | Fc1cc(F)c(F)c(OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)c1F | 500mg | 279709072
Mal-amido-PEG8-TFP ester | Broadpharm | 1924596-31-5 | MFCD28505514 | 740.699 | C32H44F4N2O13 | 98.000 | Fc1cc(F)c(F)c(OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)c1F | 500mg | 279709072
eMolecules 1263044-81-0 | m-PEG4-Mal | Broadpharm | MFCD13185020 | 358.391 | C16H26N2O7 | 98.000 | COCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 1g | 279709062
m-PEG4-Mal | Broadpharm | 1263044-81-0 | MFCD13185020 | 358.391 | C16H26N2O7 | 98.000 | COCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 1g | 279709062
eMolecules 1807540-84-6 | Mal-amido-PEG4-TFP ester | Broadpharm | MFCD28505515 | 564.487 | C24H28F4N2O9 | 95.000 | Fc1cc(F)c(F)c(OC(=O)CCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)c1F | 250mg | 279709410
Mal-amido-PEG4-TFP ester | Broadpharm | 1807540-84-6 | MFCD28505515 | 564.487 | C24H28F4N2O9 | 95.000 | Fc1cc(F)c(F)c(OC(=O)CCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)c1F | 250mg | 279709410
Medchemexpress LLC Propargyl-PEG4-5-nitrophenyl carbonate | 1422540-81-5 | 98.19% | 397.38 | 25 MG
Propargyl-PEG4-5-nitrophenyl carbonate is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It acts as a click chemistry reagent, possessing an Alkyne group that enables it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs consist of two distinct ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein, facilitating the selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
Medchemexpress LLC PC-Biotin-PEG4-NHS carbonate | 2055198-03-1 | MFCD29079395 | > 96% | 810.87 | 25 MG
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a unique amine-reactive, photocleavable biotin reagent, making it useful for introducing a biotin moiety to amine-containing molecules. This compound also serves as a linker for bio-conjugation, featuring a terminal NHS carbonate and a photocleavable biotin group, all linked through a linear PEG chain.
- PEG-based PROTAC linker
- Amine reactive
- Photocleavable biotin reagent
- Introduces biotin moiety to amine-containing molecules
- Linker for bio-conjugation
- Contains a terminal NHS carbonate
- Linked through a linear PEG chain
Medchemexpress LLC DSPE-PEG-FITC | 1000788-53-3 | 10000 Da | 5 MG
DSPE-PEG-FITC is a fluorescein-labeled PEGylated phospholipid designed for incorporation into liposomes, micelles, and other lipid-based nanoparticles to provide a green fluorescent tag for tracking and imaging in research applications.
- Average molecular weight 10,000 Da.
- Fluorescein (FITC) label provides green fluorescence for imaging.
- Suitable for liposome and nanoparticle labeling and tracking.
- Appearance: yellow to orange solid.
- Soluble in DMSO; use ultrasonic and warming up to 60°C to aid dissolution.
- In solvent stability: store at -80°C up to 6 months or -20°C up to 1 month; protect from light.
- Available in small research sizes such as 5 mg.
- Recommended in vivo formulation: 10% DMSO in 90% corn oil for administration.
Medchemexpress LLC M-PEG4-PFP ester | 2952895-31-5 | ≥98.0% | 402.31 | 100 MG
m-PEG4-PFP ester is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. These molecules are engineered to contain two distinct ligands, one binding to an E3 ubiquitin ligase and the other targeting a specific protein. This innovative design allows PROTACs to leverage the cell's ubiquitin-proteasome system for the selective degradation of target proteins.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC DSPE-PEG-COOH | No CAS number listed for this product (HY-W591461). | No MFCD number listed for this product (HY-W591461). | 100.0% | 2000 (average) | No chemical formula listed for this product (polymeric PEG; variable repeat unit). | 25 MG
DSPE-PEG-COOH, MW 2000 is a PEGylated phospholipid used to formulate liposomes and lipid nanoparticles. It is supplied as a white to off-white solid and features a terminal carboxylic acid that can be activated to form stable amide bonds with primary amines for surface conjugation. Typical storage is -20°C, sealed, away from moisture.
- Terminal carboxylic acid for amide bond conjugation.
- Suitable for liposome and lipid nanoparticle formulation.
- White to off-white solid for easy handling and weighing.
- Available in small research pack sizes for lab use.
- High purity suitable for research use (purity ≥99.9%).
Medchemexpress LLC HY-128801 100mg Medchemexpress, NH2-PEG3-C1-Boc CAS:189808-70-6 Purity:>98%
Medchemexpress, HY-128801 100mg NH2-PEG3-C1-Boc CAS:189808-70-6 NH2-PEG3-C1-Boc (PROTAC Linker 5) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.