Protein Modification Reagents
eMolecules Mal-PEG1-Val-Cit-PAB-PNP | 2249935-92-8 | | 250mg
Broadpharm | Mal-PEG1-Val-Cit-PAB-PNP | 250mg | 462125556 | BP-24314 | 98.000 | 2249935-92-8 | | 739.739 | C34H41N7O12
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Medchemexpress LLC Mal-PEG1-NHS ester | 1807518-72-4 | MFCD26127783 | 99.6% | 310.26 g/mol | C13H14N2O7 | 250 MG
Mal-PEG1-NHS ester is a PEG-based bifunctional linker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester. It is used as a non-cleavable linker for antibody-drug conjugates and as a PEG linker in PROTAC synthesis to connect thiol- and amine-containing molecules. For research use only.
- Contains maleimide and NHS ester reactive groups
- PEG1 spacer increases solubility and flexibility
- Molecular weight 310.26 g/mol; formula C13H14N2O7
- High purity (≈99.6%) suitable for conjugation reactions
- Available in small to multi-gram pack sizes, including 250 mg
- Store powder at -20°C; solvent solutions stable at -80°C (6 months)
Medchemexpress LLC Pomalidomide-peg4-c2-nh2 hydrochloride | 2357105-92-9 | 98.2% | 528.98 | 1 G
Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a 4-unit PEG linker, used in the synthesis of PROTACs. It is for research use only and not sold to patients.
- PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- These methods are for reference only.