Immunohistochemistry Kits and Reagents
ABclonal Technology Phospho-p38 MAPK-T180 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Abcam DoubleStain IHC Kit: M&R on human tissue (DAB & AP/Red), 6ML
Abcam's DoubleStain IHC Kit: M&R on human tissue (DAB & AP/Red) (ab210059) is designed to detect two distinct antigens on human tissue or cell samples using a simplified protocol with user-supplied mouse and rabbit antibodies.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology γ-Catenin Rabbit pAb
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene, however, not all transcripts have been fully described.
Immunology Consultants Hamster (CHO) Beta 2-Microglobulin - Recombinant, 0.025mg
This recombinant CHO beta‑2‑microglobulin (B2M; GenBank NP_001233603.1) is expressed in CHO‑S cells with a C‑terminal 6xHIS tag and purified by nickel affinity chromatography to >90% purity. The protein appears at ~14 kDa under reducing conditions and is quantified by Bradford assay. B2M is a well‑known CHO host cell protein that frequently co‑elutes with monoclonal antibodies due to its immunoglobulin‑like domains, making it a critical impurity to monitor in biologics manufacturing. This high‑quality recombinant antigen provides consistent purity, stability, and biological relevance for ELISA development, antibody validation, and HCP assay calibration. Ideal for teams building targeted impurity detection tools or studying CHO‑derived contaminants, this B2M standard supports reliable process monitoring and enhances confidence in downstream purification strategies.
Biogenex Laboratories Negative Control Sera/Immunoglobulins
Since each staining run should include a negative control slide to confirm reagent specificity, we offer negative control sera/immunoglobulins which have been optimized for use as negative controls for our Super Sensitive detection systems and ready-to-use antibodies. These controls are available for mouse, goat, rat and rabbit antibodies.
Abcam DoubleStain IHC Kit: G&Rt on human/mouse tissue (BCIP & AEC), 18ML
The DoubleStain IHC kit (ab183281) is designed to be used with user supplied goat and rat primary antibodies to detect two distinct antigens on human or mouse tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Tissue Clearing Reagent 1 and 2 combo - hydrophobic, 10ML
Tissue Clearing Reagent 1 and 2 combo, ab243316, contains both clearing reagents, which are components of the complete kit: Tissue Clearing Kit ab243298.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DoubleStain IHC Kit: G&M on human tissue (Green/HRP & AP/Red), 18ML
Abcam's DoubleStain IHC kit (ab183272) is designed to use with user supplied goat and mouse antibodies to detect two distinct antigens on human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Biotium Napsin A (Lung Adenocarcinoma Marker)(NAPSA/1865R), CF740 conjugate, 0.1mg/mL
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Desmin (Muscle Cell Marker)(D33), Biotin conjugate, 0.1mg/mL
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. Primary antibodies are available purified, or with a selection of fluorescent CF
Biotium Napsin A (Lung Adenocarcinoma Marker)(NAPSA/1865R), Biotin conjugate, 0.1mg/mL
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Cayman Chemical S-p38 MAPK InhIbItr III 500ug
A methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 µM in vitro); potently blocks the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 µM, respectively)
Abcam Rabbit specific HRP/DAB Detection IHC Detection Kit - Micro-polymer, 15ML
This IHC kit is used to detect rabbit primary antibodies in immunohistochemistry (IHC).
The product is subject to the following: Abcam Restricted Use Statement
