Immunohistochemistry Kits and Reagents
IBL America Complement System Screen
The Wieslab Complement system Screen kit is an enzyme immunoassay for the determination of functional classical, MBL and alternative complement pathways in human serum. For research use only, not for use in diagnostic procedures.
The complement system plays an essential role in chronic, autoimmune and infectious disease. There are three pathways of complement activation, namely the classical, the alternative and the recently discovered MBL pathway.
Impaired complement activity causes humans to become susceptible to repetitive fulminant or severe infections and may contribute to development of autoimmune disease. Inappropriate activation of complement contributes to chronic inflammation and tissue injury. For research use only, not for use in diagnostic procedures.
World Precision Instrument Kit, CABLAY ISO-DAM8A, unterminated
- Unterminated, 5' multi-strand cable on an 8-pin DIN
Revvity Health Sciences Inc AlphaLISA SureFire Ultra Multiplex Phospho-DAP12 (Tyr91 & total) Detection Kit, 10,000 Assay Points
AlphaLISA SureFire Ultra Multiplex Phospho-DAP12 (Tyr91 & total) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF mAb Anti-FLAG Tb-Conjugate, 20,000 Assay Points
HTRF mAb Anti-FLAG Tb-Conjugate, 20,000 Assay Points
Cayman Chemical p38 MAPK InhIbItr IV 5mg
An ATP-competitive inhibitor of p38 MAPKs; inhibits p38α, p38β, p38��, and p38δ MAPKs (IC50s = 0.13, 0.55, 5.47, and 8.63 μM, respectively); inhibits LPS-induced TNF-α and IL-1β cytokine production in human peripheral blood mononuclear cells (IC50s = 22 and 44 nM, respectively)
BIOHIPPO Phospho- Ser/Thr PDK1 Docking
U-Blot Phospho-(Ser/Thr) PDK1 Docking Motif Mouse mAb is a Mouse-derived recombinant monoclonal antibody (clone W-R31) that specifically recognizes Phospho-(Ser/Thr) PDK1 Docking Motif a phosphorylation modification at Serine/Threonine residues in the PDK1 docking motif It shows reactivity with Human Validated applications include WB Recommended dilutions WB 1500-11000 Purified by protein a Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine in a hydrophobic motif For example Akt a kinase that regulates cell survival is activated by phosphorylation at Ser473 a site preceded by Phe at -4 and -1 and followed by Tyr at 1 RSK2 p70 S6 kinase and certain PKC isoforms also contain a similar consensus phosphorylation motif Phosphorylation of these motifs is required for binding to 3-phosphoinositide dependent kinase 1 (PDK1) Supplied as 100 uL
Medchemexpress LLC Plasmalemma vesicle-associated protein (PLVAP), human recombinant (HEK293, His tag) | ≥95.0% | 100UG
Recombinant human plasmalemma vesicle-associated protein (PLVAP) is supplied as a lyophilized, HEK293-expressed His-tagged protein for research on endothelial barrier function and microvascular permeability. The material is provided with low endotoxin and guidance for reconstitution and storage to support biochemical and cell-based studies.
- Species: human.
- Source: HEK293 expression system.
- Tag: His tag for purification.
- Purity: ≥95.0% as determined by Tris-Bis PAGE.
- Molecular weight: 50-70 kDa.
- Formulation: lyophilized from PBS with 200 mM l-arginine and 8% trehalose.
- Endotoxin: <1 EU/μg.
- Storage: store lyophilized at -20°C; aliquot and freeze after reconstitution.
ABclonal Technology Phospho-SMO-S616 Rabbit pAb
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.
Abcam TripleStain IHC Kit: R&R&M on human tissue (DAB, AP/Red & Green/HRP), 6ML
Abcam's TripleStain IHC Kit (ab183288) is designed to be used with one mouse and two rabbit primary antibodies, supplied by the user, to detect three distinct antigens on human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Meridian Life Science Lyo-Ready Direct RNA/DNA, 50ML
Lyo-Ready RNA/DNA LAMP Saliva mix combines even greater tolerance with fast, robust isothermal amplification to enable highly sensitive direct detection using crudely processed saliva or sputum samples. The mix is uniquely designed to overcome much higher concentrations of inhibitors, and so do not require a DNA or RNA purification step to concentrate and purify a patient sample. Very fast reaction kinetics result in faster time to results and superior amplification sensitivity and specificity. In addition, the 4x concentrated master mix is formulated with lyo-excipients which are optimized for freeze-drying to create ambient-temperature stable assays, making it ideal for POC saliva testing.
Biotium Bax(2D2), CF594 conjugate, 0.1mg/mL
This antibody recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Sino Biological Recombinant Human Cadherin-16 Protein (His Tag), Biotinylated 20 µg
A DNA sequence encoding the Human Cadherin-16 (NP_004053.1) (Met1-Ala786) was expressed with a polyhistidine tag at the C-terminus. The purified protein was biotinylated in vitro.
ABclonal Technology KO Validated Claudin 1
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet with complementary grooves in the inwardly facing extracytoplasmic leaflet The protein encoded by this gene a member of the claudin family is an integral membrane protein and a component of tight junction strands Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome
Meridian Life Science Lyo-Ready Direct RNA/DNA, 5ML
Lyo-Ready RNA/DNA qPCR Blood is a 4x qPCR master mix for the development of both DNA and RNA blood tests from whole blood, plasma and serum samples. The mix has been formulated specifically to overcome the inhibitors found in blood samples – no further optimization is required aside from the addition of primers and probes. Furthermore, these mixes can be used in a wet format or lyophilized to create ambient-temperature stable whole blood tests, plasma tests or serum tests.