Immunohistochemistry Kits and Reagents
ABclonal Technology Phospho-PDK1/PDPK1-S241 Rabbit pAb
Enables 3-phosphoinositide-dependent protein kinase activity, phospholipase activator activity, and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway, regulation of protein kinase activity, and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection, cytosol, and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma.
Biotium CD45RO(UCHL-1), CF594 conjugate, 0.1mg/mL
Recognizes a 180-185 kDa protein, identified as isoform of leukocyte common antigen (CD45RO) (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
ABclonal Technology SYNPO Rabbit pAb
Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the proteins associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).
Meridian Life Science Lyo-Ready LAMP Mix 4x, 5ML
Lyo-Ready LAMP Mix 4x is a glycerol-free mix for use in loop-mediated isothermal amplification (LAMP). It combines the latest advances in buffer chemistry and reaction enhancers, together with an optimized concentration of strand-displacing Polymerase, dNTP and proprietary lyo-excipients allowing ambient temperature stabilization through lyophilization. Lyo-Ready LAMP Mix has been designed for fast, sensitive and highly reproducible DNA target amplification. In order to produce lyophilized ambient-temperature stable LAMP assays, specific primers need to be added prior to lyophilization.
Biotium NKX2.2(NX2/294), CF594 conjugate, 0.1mg/mL
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium MALT-1(MT1/410), CF594 conjugate, 0.1mg/mL
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not re
American Research Products Inc PrEST Antigen CR1
PrEST Antigen CR1 antigen APrEST83626 for complement component (3b/4b) receptor 1 (Knops blood group) Recombinant protein fragment of Human CR1
American Research Products Inc PrEST Antigen CR1
PrEST Antigen CR1 antigen APrEST83625 for complement component (3b/4b) receptor 1 (Knops blood group) Recombinant protein fragment of Human CR1
American Research Products Inc PrEST Antigen PTPRO
PrEST Antigen PTPRO antigen APrEST85216 for protein tyrosine phosphatase receptor type O Recombinant protein fragment of Human PTPRO
American Research Products Inc PrEST Antigen RHAG
PrEST Antigen RHAG antigen APrEST86045 for Rh-associated glycoprotein Recombinant protein fragment of Human RHAG