Mass-Tagged Crosslinkers
Cayman Chemical HypoxnthIn-d4 25mg
An analytical reference standard that is structurally similar to known synthetic cannabinoids intended for research and forensic applications
Cayman Chemical HypoxnthIn-d4 50mg
An analytical reference standard that is structurally similar to known synthetic cannabinoids intended for research and forensic applications
Cayman Chemical HypoxnthIn-d4 10mg
A nitric oxide-donating derivative of 17-phenyl trinor PGF2a reduces IOP in a rabbit model of hypertonic saline-induced transient ocular hypertension at 0 14 reduces IOP in a cynomolgus monkey model of laser-induced ocular hypertension at 0 042
Cayman Chemical L-KynurenIn-d4 5mg
A nitric oxide-donating derivative of 17-phenyl trinor PGF2a reduces IOP in a rabbit model of hypertonic saline-induced transient ocular hypertension at 0 14 reduces IOP in a cynomolgus monkey model of laser-induced ocular hypertension at 0 042
Cayman Chemical N-NItrosonrnIcotIn-d4 10mg
A carbohydrate starting material has been used as a starting material in the synthesis of L-nucleoside-based anti-HIV agents
Cayman Chemical AbIrateron Acetate-d4 5mg
A P2Y12 receptor antagonist inhibits collagen- arachidonic acid- and ADP-induced aggregation of human platelets (IC50s 75 600 and 1300 M respectively) inhibits ADP-induced aggregation of rat platelets decreases thrombus weight in a rat model of arterio-venous shunt thrombosis at 100 mg/kg inhibits healing of acetic acid-induced gastric ulcers in rats at 300 mg/kg
Cayman Chemical Dexamethason-d4 10mg
A quinolone antibiotic active against E coli Pasturella K pneumoniae A aerogenes Proteus Salmonella and Shigella (MBCs 0 5-25 Ug/ml) increases survival in mouse models of systemic K pneumoniae A aerogenes Proteus or Salmonella infection (ED50s 60 35 50 and 62 mg/kg respectively)
Cayman Chemical AloIsolIthocholIc AcId-d4 5mg
A PDE4D negative allosteric modulator (IC50 28 nM for the human enzyme) selective for PDE4D over PDE4B (IC50 562 nM for the human enzyme) as well as 14 other PDE isoforms (IC50s 1.4 UM) decreases forskolin-induced cAMP hydrolysis in HEK293 cells (IC50 253 nM) and dextran gel-induced increases in leukotriene E4 production in isolated human whole blood (IC50 44 nM) impairs novel object recognition in mice at 3 mg/kg but does not increase anesthesia duration a proxy measure of emesis induction in mice at 3 or 10 mg/kg
Cayman Chemical MoclobemIde-d4 25mg
An ASIC3 activator (EC50 67 UM for evoking rapid inward currents in ASIC3-expressing CHO cells at neutral pH) an inhibitor of the GABAA receptor (IC50 0.39 UM in primary rat hippocampal neurons) increases paw licking time in Asic3 / and to a lesser extent Asic3-/- mice at 100 UM
Cayman Chemical S-AdenosylhomocysteIn-d4 5mg
Recombinant SARS-CoV-2 N-terminal His-tagged nsp10 expressed in E. coli Amino acids 1-139 (full length)
Cayman Chemical GlycodeoxycholIc AcId-d4 5mg
An internal standard for the quantification of dovitinib by GC- or LC-MS
Cayman Chemical ChenodeoxycholIc AcId-d4 5mg
A phenethylamine whose physiological and toxicological properties have not been investigated intended for research and forensic applications