Mass-Tagged Crosslinkers
Cayman Chemical DMABA-d4 NHS ester 25mg
A stable analog of 9-THC and AEA exhibits high-affinity for the CB1 and CB2 receptors (Ki 210 and 30 nM respectively) behaves primarily as a CB1 receptor partial agonist and a CB2 receptor neutral antagonist in vitro
Cayman Chemical Sulfamethoxazole-d4 1mg
A ferroptosis inhibitor inhibits erastin-induced cell death in HT-1080 cells from 0 01-1 M contains a diyne small vibrational tag and has been used to assess localization of ferrostatin-1 in HT-1080 cells using stimulated Ramen scattering microscopy
Cayman Chemical DMABA-d4 NHS ester 5mg
An internal standard for the quantification of abnormal cannabidiol by GC- or LC-MS intended for research and forensic applications
Cayman Chemical 5-BromopentnoIc AcId-d4 5mg
An inhibitor of GLS1 (IC50 0 021 M) inhibits the growth of NCI H1703 NSCLC cells in vitro (GI50 0 011 M) reduces tumor growth increases tumor levels of glutamine and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model at 100 mg/kg
Cayman Chemical AlolIthocholIc AcId-d4 5mg
A linoleic acid metabolite induces chemotaxis increases the levels of CCR9 and CXCR4 and inhibits IL-6 release in primary human monocytes inhibits CD3a- and CD28-induced proliferation of isolated human peripheral blood lymphocytes at 25 Ug/ml
Cayman Chemical DMABA-d4 NHS ester 1mg
An internal standard for the quantification of abnormal cannabidiol by GC- or LC-MS intended for research and forensic applications
Cayman Chemical DMABA-d4 NHS ester 10mg
A stable analog of 9-THC and AEA exhibits high-affinity for the CB1 and CB2 receptors (Ki 210 and 30 nM respectively) behaves primarily as a CB1 receptor partial agonist and a CB2 receptor neutral antagonist in vitro
Cayman Chemical AloIsolIthocholIc AcId-d4 5mg
A PDE4D negative allosteric modulator (IC50 28 nM for the human enzyme) selective for PDE4D over PDE4B (IC50 562 nM for the human enzyme) as well as 14 other PDE isoforms (IC50s 1.4 UM) decreases forskolin-induced cAMP hydrolysis in HEK293 cells (IC50 253 nM) and dextran gel-induced increases in leukotriene E4 production in isolated human whole blood (IC50 44 nM) impairs novel object recognition in mice at 3 mg/kg but does not increase anesthesia duration a proxy measure of emesis induction in mice at 3 or 10 mg/kg