A highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Shows an anti-proliferative activity against a variety of tumor cell lines. WYE-132 causes inhibition of protein synthesis and cell size, induction of apoptosis, and cell cycle progression. Alternative name: 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea, WYE-125132. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.