General Cell Based Assays
Abcam Glutathione Peroxidase Activity Assay Kit (Fluorometric)
Glutathione Peroxidase Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical LDH Cytotoxicity Assay Kit, 96 Well
For measurement of LDH activity as an indicator of cell death
ACROBiosystems Human Fc gamma RIIIA / CD16a (V176) binding Kit (TR-FRET) is expressed from Human, 100 tests
Human Fc gamma RIIIA / CD16a (V176) binding Kit (TR-FRET) is expressed from Human
Cayman Chemical LipidLaunch™ LNP-0315 Uptake Kit (Near-Infrared Fluorescence), 1 ea
Cayman’s LipidLaunch™ LNP-0315 Uptake Kit (Near-Infrared Fluorescence) is intended to serve as a starting point for laboratories to explore the uptake of LNPs in vivo without the need for specialized equipment. Optimal preparation conditions for the encapsulation of nucleic acids with LNPs must be determined by the end user.
Sigma Aldrich Fine Chemicals Biosciences Ras Assay Reagent Raf 1 RB
Product Source Human Ras Binding Domain (RBD residues 1-149) of Raf-1 expressed in E. coli.
Eurofins Discoverx cAMP Hunter eXpress GLP1R CHO-K1 GPCR Assay, 2-Plate Kit. (95-0062E2CP2M)
The cAMP Hunter GLP1R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. exendin-4) based activation of GLP1R GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GLP1R, a naturally Gs coupled GPCR. Upon activation of GLP1R, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Dojindo Molecular Technologies Inc DNA DAMAGE QUANTIFIC KIT (20 SAMPLES) is a colorimetric microplate assay and can determine the number of abasic sites in genomic DNA samples.
Oxidative damage to DNA is a result of its interaction with reactive oxygen species (ROS), in particular the hydroxy radical. Hydroxy radicals, which are produced from superoxide anion and hydrogen peroxide by the Fenton reaction, produce multiple modifications in DNA. Oxidative attacks by hydroxy radicals on the deoxyribose moiety leads to the release of free bases from DNA, generating strand breaks with various sugar modifications and simple abasic sites (AP sites). In fact, AP sites are one of the major types of damage generated by ROS. The Aldehyde Reactive Probe reacts specifically with an aldehyde group present on the open ring form of the AP sites. DNA Damage Quantification Kit contains all the necessary solutions for detecting between 1 to 40 AP sites per 1 x 105 base pairs.
Dojindo Molecular Technologies Inc Cellular Senescence Detection Kit (1 plate), detects SA-β-gal with high sensitivity, applicable to both living and fixed cells, for cell sample by fluorescence microscopy or flow cytometry.
SPiDER-βGal is a new reagent to detect β-galactosidase specifically which possesses a high cell-permeability and a high retentivity inside cells. This novel reagent can detect β-galactosidase not only in fixed cells but also in living cells, and also can be applied to quantitative analysis by flow cytometry. Senescence-associated beta-galactosidase (SA-β-gal), which is overexpressed in senescent cells, has been widely used as a marker of cellular senescence. Cellular Senescence Detection Kit – SPiDER-βGal is optimized to detect intracellular SA-β-gal. Modern publications with a high number of citations summarize the various features of cellular senescence on the following page (https://www.dojindo.com/senescent-cell-detection-selection-guide/).
Abcam DNMT3B Assay Kit.
DNMT3B Assay Kit.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter OSMRb/IL31R Bioassay Kit, 2-Plate. (93-1002Y3-00083)
The PathHunter OSMRb/IL31R Dimerization Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. IL-31) induced dimerization of OSMRb/IL31R receptors. This product uses EFC technology. The cell line included overexpresses OSMRb target protein fused to PK alongside IL31RA target protein fused to EA. Upon ligand-induced dimerization of OSMRb/IL31R, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Revvity Health Sciences Inc HTRF Human & Mouse Total Histone H3 Detection Kit, 500 Assay Points
HTRF Human & Mouse Total Histone H3 Detection Kit, 500 Assay Points
ACROBiosystems Human Fc gamma RIIA / CD32a (R167) binding Kit (TR-FRET) is expressed from Human, 10000 tests
Human Fc gamma RIIA / CD32a (R167) binding Kit (TR-FRET) is expressed from Human
ACROBiosystems Human Fc gamma RIIA / CD32a (R167) binding Kit (TR-FRET) is expressed from Human, 100 tests
Human Fc gamma RIIA / CD32a (R167) binding Kit (TR-FRET) is expressed from Human
Eurofins Discoverx PathHunter eXpress rVIPR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0913E2RCP2L)
The PathHunter rVIPR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. VIP) based activation of rVIPR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rVIPR1 and EA-tagged β-Arrestin-2. Activation of rVIPR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.