General Cell Based Assays
Meso Scale Discovery RPLEX HUM Cathepsin L2 ASYQP
The R-PLEX Human Cathepsin L2 Assay is a multiplex immunoassay kit from Meso Scale Diagnostics that allows for the quantitative measurement of human Cathepsin L2 in serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements This assay kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL tag calibrators and diluents needed to perform the assay It can detect Cathepsin L2 concentrations as low as 3 2 pg/mL with an upper limit of 100 000 pg/mL
Eurofins Discoverx cAMP Hunter™ Human GPR109A Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human GPR109A Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR109A (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human c-Ret-GFR alpha 2 Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human c-Ret-GFR alpha 2 Stable Cell Line Functional Kinase Assay (U2OS) measures c-Ret-GFRα2 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress HTR2C U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0289E3CP3M)
The PathHunter HTR2C eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. serotonin) based activation of HTR2C GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR2C and EA-tagged β-Arrestin-2. Activation of HTR2C stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human SCTR Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human SCTR Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure SCTR (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Genscript Corporation ToxinSensor Single Tests Kit
GenScript ToxinSensor Single Tests Kit with Standard is designed to be a qualitative In Vitro end-point endotoxin test for human and animal parenteral drugs biological products and medical devices Tachypleus Amebocyte Lysate (TAL) as supplied is to be reconstituted with sample or control directly After incubation for 1 hour and in the presence of endotoxin gelation occurs in the absence of endotoxin gelation does not occur GenScript supply a series of ToxinSensorTM Single Tests Kits with Standard with different sensitivity (0 03 EU/ml 0 06 EU/ml 0 125 EU/ml and 0 25 EU/ml)
Eurofins Discoverx PathHunter eXpress MC4R U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0211E3CP0M)
The PathHunter MC4R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-MSH) based activation of MC4R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC4R and EA-tagged β-Arrestin-2. Activation of MC4R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ABclonal Technology LDH-B
This gene encodes the B subunit of lactate dehydrogenase enzyme which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD in a post-glycolysis process Alternatively spliced transcript variants have been found for this gene Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism and that this isoform is localized in the peroxisomes Mutations in this gene are associated with lactate dehydrogenase B deficiency Pseudogenes have been identified on chromosomes X 5 and 13
Eurofins Discoverx cAMP Hunter eXpress LHCGR CHO-K1 GPCR Assay, 10-Plate Kit. (95-0106E2CP2L)
The cAMP Hunter LHCGR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. luteinizing hormone) based activation of LHCGR GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type LHCGR, a naturally Gs coupled GPCR. Upon activation of LHCGR, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress PTHR1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0315E2CP0M)
The PathHunter PTHR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. PTH) based activation of PTHR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTHR1 and EA-tagged β-Arrestin-2. Activation of PTHR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Microsolv Technology Corporation Base Plate, Translucent Polypropylene, Micro-Sample Management System, universal, re-usable. 6/PK.
Accommodates and holds one Micro-Sample Insert Rack in the U-2D System. Made of low weight polypropylene plastic, they comply with ANSI standards for 96 well plates. When used with Racks of Inserts, the unique molded bottoms allow each insert to be supported on the bottom. Use in a vortex mixer or water bath can be used with enhanced performance. Also most plate readers can be used. Bases are reusable and can be refrigerated.
Revvity Health Sciences Inc AlphaScreen FITC Detection Kit, 500 Assay Points
AlphaScreen FITC Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human FMRP Detection Kit, 500 Assay Points
HTRF Human FMRP Detection Kit, 500 Assay Points
Cayman Chemical a-D-Glucose-1-phosphatesodI 5g
An intermediate in glycogen metabolism; precursor in the biosynthesis of UDP-glucose; can be formed during glycogen breakdown via phosphorolytic cleavage of glycogen by glycogen phosphorylase; can be converted to glucose-6-phosphate by phosphoglucomutase; is combined with CTP to form CDP-glucose in S. typhi
ABclonal Technology HRH2 Rabbit pAb
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.