General Cell Based Assays
Discovery Life Sciences Gentest Sprague DawlRat Hep
Gentest Sprague Dawley Rat Hepatocytes Cryopreserved Male Plateable Inducible
Meso Scale Discovery U-PLEX Mouse IL-6 ASY
The Meso Scale Discovery U-PLEX Mouse IL-6 Assay Kit is a multiplex immunoassay for measuring mouse interleukin 6 (IL-6) in various biological samples It uses electrochemiluminescence (ECL) detection for high sensitivity and precision The kit includes a 96-well plate with capture antibodies ECL-tagged detection antibodies calibrators and diluent The assay takes about 3 5 hours and requires a Meso Scale Discovery instrument It detects IL-6 with a lower limit of 0 3 pg/mL allowing quantitation across a wide range
Abcam Acetoacetate Assay Kit (Colorimetric)
Acetoacetate Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Swinholide A, F-actin inhibitor, 10UG
MW 1389.9 Da, Purity >97%. Cell permeable, selective F-actin inhibitor. Sequesters and stabilizes actin dimers. Induces actin depolymerization and apoptosis. .
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress CXCR1 (IL8RA) U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0226E3CP0M)
The PathHunter CXCR1 (IL8RA) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL8/IL8) based activation of CXCR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR1 and EA-tagged β-Arrestin-2. Activation of CXCR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CHRM2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0198E2CP0M)
The PathHunter CHRM2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. oxotremorine) based activation of CHRM2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CHRM2 and EA-tagged β-Arrestin-2. Activation of CHRM2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical NADP+ (hydrate), Purity: ≥90%, 250 mg
The oxidized form of NADPH; serves as a cofactor in various biological reactions
Eurofins Discoverx PathHunter Human IL-15 (IL-15R (IL2RB/IL2RG)) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-15 (IL-15R (IL2RB/IL2RG)) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL2RB/IL2RG. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
American Research Products Inc HOXB2 Transcription Factor Activity Assay
HOXB2 Transcription Factor Activity Assay
Abcam Sodium Assay Kit (Colorimetric)
Sodium Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Molecular Devices QBT Fatty Acid Uptake Assay, Bulk, BODIPY-dodecanoic, 96/384-well
The QBT Fatty Acid Uptake Assay Kit is a homogeneous, fluorescence-based assay for measuring live-cell fatty acid uptake kinetics and screening fatty acid transporters in high-throughput formats. The assay uses a fluorescent fatty acid analog with a quench reagent to reduce extracellular background and enable kinetic readings.
- Homogeneous fluorescence assay suitable for high-throughput screening.
- Uses a BODIPY-dodecanoic fluorescent fatty acid analog and quench reagent.
- Bulk kit contains 10 vials, sufficient for approximately 50 plates.
- Compatible with 96-well and 384-well microplate formats.
- Measure kinetics with bottom-read fluorescence, excitation ~470-500 nm, emission ~500-560 nm.
- Store kit at -20°C; formulated loading buffer stable up to 8 hours at room temperature.
Eurofins Discoverx PathHunter eXpress PTGFR Total Internalization Assay, 2pl Kit. (93-0872E3CP0M)
The PathHunter PTGFR Total Internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of PTGFR via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged PTGFR and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the PTGFR receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR162 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0383E2ACP1M)
The PathHunter GPR162 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR162 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR162 and EA-tagged β-Arrestin-2. Activation of GPR162 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical NFAT Inhibitor, Purity: ≥95%, CAS: 249537-73-3, 10 mg
A peptide inhibitor of NFAT; binds to the NFAT recognition site on calcineurin (IC50 = 25 pM) but does not inhibit calcineurin phosphatase activity at 100 µM; inhibits the dephosphorylation of NFAT in HEK293T lysates expressing NFAT1, -2, or -4; inhibits NFAT activation in RAW 264.7 macrophages, EA.hy926 endothelial cells, and isolated mouse thoracic aorta VSMCs (IC50s = 29.1, 30.2, and 45.7 µM, respectively, in reporter assays)
Eurofins Discoverx PathHunter eXpress KDR/KDR Dimerization Assay, 10-Plate Kit. (93-0996E1CP0L)
The PathHunter KDR/KDR Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. VEGF-121) induced dimerization of KDR/KDR receptors. This product uses EFC technology. The cell line included overexpresses KDR target protein fused to PK alongside KDR target protein fused to EA. Upon ligand-induced dimerization of KDR/KDR, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.