General Cell Based Assays
Eurofins Discoverx PathHunter Human GPR103 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR103 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR103 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human BMP-6 (BMPR1B/BMPR2) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human BMP-6 (BMPR1B/BMPR2) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of BMPR1B/BMPR2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Bioss KD-Validated Actin like 6A Rab
Actin Like 6A Primary Antibody Unconjugated Public Immunogen Range 210-274/429 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Sigma Aldrich Fine Chemicals Biosciences Mitochondrial Membrane Pot
Mitochondria generate a potential across their membranes due to the activities of enzymes of the electron transport chain. During apoptosis collapse of the mitochondrial membrane potential (MMP) coincides with the opening of the mitochondrial permeability transition pores leading to the release of cytochrome c into the cytosol which in turn triggers other downstream events in the apoptotic cascade.
Eurofins Discoverx PathHunter eXpress OPRL1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0264E2CP0M)
The PathHunter OPRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. orphanin FQ) based activation of OPRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRL1 and EA-tagged β-Arrestin-2. Activation of OPRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Medchemexpress LLC cGAS Human His-SUM 5ug
The cGAS protein is a nucleotidyl transferase that crucially mediates innate immunity by catalyzing the formation of 2 3 -cGAMP from ATP and GTP upon binding to double-stranded DNA (dsDNA) As a DNA sensor cGAS detects exogenous and endogenous DNA triggering STING1 activation and type I interferon production cGAS Protein Human (His-SUMO) is the recombinant human-derived cGAS protein expressed by E coli with N-6 His N-SUMO labeled tag
Cayman Chemical GPX4 GlutathIon Reductase 1ea
GPX4 Glutathione Reductase has been tested and formulated to work exclusively with Cayman’s GPX4 Inhibitor Screening Assay Kit (Item No. 701880).
Arbor Assays Glutathione Fluorescent Detection Kit (5 Plate)
The DetectX Glutathione (GSH) Fluorescent Detection Kit utilizes a proprietary non-fluorescent molecule, ThioStar, that covalently binds to the free thiol group on GSH to yield a highly fluorescent product.
Eurofins Discoverx PathHunter Mouse IL-8 (CXCR2) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse IL-8 (CXCR2) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure mCXCR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Bioassay Systems EnzyFluo™ Acetaldehyde Assay Kit. For quantitatve determination of acetaldehyde and evaluations of drug effects on its metabolism.
For quantitatve determination of acetaldehyde and evaluations of drug effects on its metabolism. Key Features: Fast and sensitive. Linear detection range (50µL sample): 0.5 µM to 60 µM acetaldehyde in 96-well plate assay. High-throughput. The procedure involves adding a single working reagent, and reading the absorbance after 30 minutes. Room temperature assay. No 37°C heater is needed. Convenient. Homogeneous "mix-incubate-measure" type assay. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day. Method: FL530/585nm. Samples: Biological samples (e.g. plasma, serum, urine, tissue and culture media) and food/beverage samples (e.g. wine, coffee, and juice). Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests. Detection limit: 0.5 µM.
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-SMAD1 (Ser463/465) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-SMAD1 (Ser463/465) Detection Kit, 50,000 Assay Points
Eurofins Discoverx PathHunter eXpress ADRB2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0182E2CP0M)
The PathHunter ADRB2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. isoproterenol) based activation of ADRB2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged ADRB2 and EA-tagged β-Arrestin-2. Activation of ADRB2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human SSTR2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human SSTR2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure SSTR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Meso Scale Discovery R-PLEX Rat KC/GRO ASY
The R-PLEX Rat KC/GRO Assay from Meso Scale Diagnostics is a multiplex immunoassay kit for measuring rat keratinocyte chemoattractant (KC) and growth-regulated oncogene (GRO) in various samples It uses electrochemiluminescence (ECL) and MSD s MULTI-ARRAY technology offering high sensitivity and a wide dynamic range The kit includes a 96-well plate with specific capture antibodies detection antibodies and calibrators Results are read on MSD platforms and analyzed with MSD Discovery Workbench software enabling efficient analysis of these neutrophil chemoattractants
Eurofins Discoverx PathHunter Human PR beta Nuclear Receptor Protein Interaction Cell-Based Assay Kit (U2OS)
The PathHunter Human PR beta Nuclear Receptor Stable Cell Line Protein Interaction Assay (U2OS) contains a stable clonal cell line used to measure activated PRβ nuclear hormone receptor interaction with SRCPs. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.