General Cell Based Assays
Eurofins Discoverx PathHunter Human TYK2 Kinase Activity Cell-Based Assay Kit (U2OS)
The PathHunter Human TYK2 Stable Cell Line Kinase Activity Assay (U2OS) measures TYK2 CTK activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical Cel-Based asy TBS10X 10mL
A NUDT15 inhibitor (IC50 25 nM) selective for NUDT15 over a panel of additional Nudix family hydrolases proteins and nucleotide pyrophosphatases at 100 UM as well as a panel of 44 kinases at 10 UM enhances thiopurine-induced cell death in NB4 and HL-60 cancer cells in a NUDT15-dependent manner
Revvity Health Sciences Inc HTRF Human Total PLC-γ2 Detection Kit, 50,000 Assay Points
HTRF Human Total PLC-γ2 Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Total c-Src Detection Kit, 500 Assay Points
HTRF Human & Mouse Total c-Src Detection Kit, 500 Assay Points
Montana Molecular Green Gi cADDis cAMP sensor Big Sky BacMam 5mL
Detect cAMP Gi signaling kinetics in living cells with the Green Gi cADDis fluorescent cAMP assay. Packaged in Big Sky BacMam, for enhanced expression in HEKs, CHOs, and many other mammalian cell types and iPSCs. This product is an update to product X0200G, with improved expression efficiency from Big Sky BacMam.
Bellbrook Labs Transcreener dAMP Exonuclease FP Assay
The Transcreener dAMP Exonuclease FP Assay is a biochemical activity assay that measures the dAMP produced by exonuclease enzymes. This kit contains detection reagents for 10,000 assay wells in a 384-well format. The assay is designed for HTS, Hit-to-Lead, SAR, and general discovery and can be used with any plate reader that measures fluorescence polarization.
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-NF-κB (Ser536) Detection Kit, 500 Assay Points
HTRF Human & Mouse Phospho-NF-κB (Ser536) Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF CD64 Cellular Binding Kit, 500 Assay Points
HTRF CD64 Cellular Binding Kit, 500 Assay Points
Aat Bioquest Amplite™ Fluorimetric Catalase Assay Kit *Red Fluorescence*
Catalase is a common antioxidant heme-containing redox enzyme found in nearly all living organisms that are exposed to oxygen. The enzyme is concentrated in the peroxisome subcellular organelles.
Revvity Health Sciences Inc AlphaLISA SureFire Ultra Multiplex Human & Mouse Phospho-SMAD2 (Ser465/467 & Total) Detection Kit, 500 Assay Points
AlphaLISA SureFire Ultra Multiplex Human & Mouse Phospho-SMAD2 (Ser465/467 & Total) Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress GIPR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-1095E2CP2M)
The PathHunter GIPR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. GIP) based activation of GIPR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GIPR and EA-tagged β-Arrestin-2. Activation of GIPR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.