General Cell Based Assays
Meso Scale Discovery U-PLEX Mouse IL-16 ASY
The Meso Scale Discovery U-PLEX Mouse IL-16 Assay is a multiplex immunoassay kit that enables simultaneous quantification of mouse interleukin 16 (IL-16) in serum plasma and cell culture supernatants This electrochemiluminescent assay utilizes MSD s proprietary SECTOR Imager and provides high sensitivity a wide dynamic range and requires low sample volume The kit includes a 96-well plate pre-coated with capture antibodies detection antibodies calibrators and controls for generating a standard curve and measuring IL-16 levels accurately This assay allows efficient reproducible analysis of IL-16 an immunomodulatory cytokine involved in inflammatory and autoimmune responses
Eurofins Discoverx PathHunter Mouse OPRM1 (Opioid mu) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Mouse OPRM1 (Opioid mu) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure mOPRM1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human IL-7 (IL7R/IL2RG) Dimerization Cell-Based Assay Kit (DLD1)
The PathHunter Human IL-7 (IL7R/IL2RG) Stable Cell Line Dimerization Assay (DLD1) measures ligand-induced dimerization of IL7R/IL2RG. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Meso Scale Discovery R-PLEX Human IL-22R 2 ASY
The Meso Scale Discovery R-PLEX Human IL-22Ralpha2 Assay is a multiplex immunoassay that measures IL-22Ralpha2 in human serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5-logs of dynamic range and low sample volume requirements The assay can be multiplexed with other R-PLEX assays to analyze multiple biomarkers simultaneously This allows efficient and accurate quantification of IL-22Ralpha2 levels alongside other immune response markers With a testing time of just 3 5 hours this assay enables rapid profiling of IL-22Ralpha2
Eurofins Discoverx PathHunter Human RANK/IkB Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human RANK IkB Stable Cell Line Functional Kinase Assay (U2OS) measures pathway activation-induced degradation of IκB target protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human LPA3 (EDG7) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human LPA3 (EDG7) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure EDG7 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress IL17RA/IL17RC Dimerization Assay, 2-Plate Kit. (93-0999E3CP0M)
The PathHunter IL17RA/IL17RC (U2OS) Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-17a) induced dimerization of IL17RA/IL17RC (U2OS) receptors. This product uses EFC technology. The cell line included overexpresses IL17RC target protein fused to PK alongside IL17RA target protein fused to EA. Upon ligand-induced dimerization of IL17RA/IL17RC, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx InCELL Hunter eXpress HEK 293 BRD3(1,2) Bromodomain Assay, 10-plate Kit. (96-0038E1CP7L)
The InCELL Hunter eXpress HEK 293 BRD3(1,2) Bromodomain Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with regulators of epigenetics pathways. This kit assesses compound-engagement-based stabilization of BRD3(1,2) via detection of BRD3(1,2) levels. This product uses EFC technology. The cell line included overexpresses BRD3(1,2) target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter™ Human SDF-1 alpha (CXCR4) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human SDF-1 alpha (CXCR4) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CXCR4 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Meso Scale Discovery U-PLEX Mouse IL-9 ASY
The Meso Scale Discovery U-PLEX Mouse IL-9 Assay Kit is an electrochemiluminescent immunoassay for the quantitative measurement of mouse interleukin 9 (IL-9) in serum plasma and cell culture supernatants The assay uses MSD s proprietary SULFO-TAG labels and multi-array technology to provide sensitive and reproducible quantitation of mouse IL-9 with a lower limit of detection of 0 3 pg/mL and an upper limit of 10 000 pg/mL The kit includes a 96-well plate coated with capture antibody detection antibody conjugated to MSD SULFO-TAG calibrators and sample diluent The assay takes approximately 3 5 hours to complete after a 2 hour incubation
Revvity Health Sciences Inc AlphaScreen FITC Detection Kit, 50,000 Assay Points
AlphaScreen FITC Detection Kit, 50,000 Assay Points
ABclonal Technology Phospho-CRMP2/DPYSL2-T514 Rabbit pAb
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimers disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Eurofins Discoverx PathHunter Human EphA4 Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human EphA4 Stable Cell Line Functional Kinase Assay (U2OS) measures EphA4 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse SDF-1 alpha (CXCR7) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Mouse SDF-1 alpha (CXCR7) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure mCXCR7 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.