General Cell Based Assays
Eurofins Discoverx PathHunter Human DRD1 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human DRD1 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure DRD1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse MIP-1 alpha (CCR5) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse MIP-1 alpha (CCR5) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCR5 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human RXFP1 Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human RXFP1 Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure RXFP1 (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human RANKL (RANK) Signaling Reporter Cell-Based Assay Kit (U2OS)
The PathHunter Human RANKL (RANK) Signaling NF-kB Reporter Stable Cell Line Assay (U2OS) measures NF-kB pathway activation through detection of induced expression levels of a tagged reporter protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human Signaling Reporter Cell-Based Assay Kit (HEK293)
The PathHunter Human IFN gamma Signaling IRF1/GAS Reporter Stable Cell Line Assay (HEK293) monitor the activation of specific signaling pathways, utilizing the established PathHunter Enzyme Fragment Complementation (EFC) technology. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human AR Nuclear Receptor Protein Interaction Cell-Based Assay Kit (CHO-K1)
The PathHunter Human AR Nuclear Receptor Stable Cell Line Protein Interaction Assay (CHO-K1) contains a stable clonal cell line used to measure activated AR nuclear hormone receptor interaction with SRCPs. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Mouse RXFP1 Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Mouse RXFP1 Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure mouse RXFP1 (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human TORC2 (CRTC2) Nuclear Translocation Cell-Based Assay Kit (U2OS)
The PathHunter Human TORC2 (CRTC2) Stable Cell Line Nuclear Translocation Assay (U2OS) contains a stable clonal cell line used to measure CRTC/CREB pathway activation via nuclear translocation of TORC2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human FPRL1 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human FPRL1 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure FPRL1 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse MIP-3 beta (CCR7) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse MIP-3 beta (CCR7) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure mCCR7 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human AHR Nuclear Receptor Protein Interaction Cell-Based Assay Kit (U2OS)
The PathHunter Human AHR Nuclear Receptor Stable Cell Line Protein Interaction Assay (U2OS) contains a stable clonal cell line used to measure activated ARH nuclear hormone receptor interaction with SRCPs. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human PTGDR Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human PTGDR Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure PTGDR (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter eXpress CNR2 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0183E2CP2M)
The cAMP Hunter CNR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CP 55,940) based activation of CNR2 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CNR2, a naturally Gi/Go coupled GPCR. Upon activation of CNR2, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human S1P1 (EDG1) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human S1P1 (EDG1) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure EDG1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR146 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR146 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR146 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.