General Cell Based Assays
Sigma Aldrich Fine Chemicals Biosciences Direct DetectR Assay free
Quantity OptionsDDAC00010-GR 50 CardsDDAC00010-4P 200 CardsDDAC00010-8P 400 CardsThe Direct Detect Assay-free Cards are desgined for use in the the Direct Detect Spectrometer. The card contains four hydrophilic polytetrafluoroethylene (PTfE) membrane positions sized for easy sample application and surrounded by a hydrophobic ring to retain analyzed sample within the IR beam. A 2 muL sample volume is recommended in order to assure proper sample application drying and measurement.The Assay-free card can be inserted into the system and analyzed immediately after preparation. The Direct Detect spectrometer has a built in drying system that will automatically dry the sample to the point where it will give an accurate reading. The Direct Detect Assay-free card is intended for a one-time protein application however already prepared cards can be stored and reread later.
Eurofins Discoverx cAMP Hunter eXpress MC3R CHO-K1 GPCR Assay, 10-Plate Kit. (95-0045E2CP2L)
The cAMP Hunter MC3R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-melanocyte stimulating hormone) based activation of MC3R GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type MC3R, a naturally Gs coupled GPCR. Upon activation of MC3R, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress SSTR5 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0402E3CP0M)
The PathHunter SSTR5 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin) based activation of SSTR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR5 and EA-tagged β-Arrestin-2. Activation of SSTR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress PROKR1 Total GPCR Internalization Assay, 10pl Kit. (93-0764E3CP0L)
The PathHunter PROKR1 Total GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of PROKR1 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged PROKR1 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the PROKR1 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CSF1R/CSF1R Dimerization Assay, 10pl Kit. (93-1061E3CP5L)
The PathHunter CSF1R/CSF1R Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. M-CSF) induced dimerization of CSF1R/CSF1R receptors. This product uses EFC technology. The cell line included overexpresses CSF1R target protein fused to PK alongside CSF1R target protein fused to EA. Upon ligand-induced dimerization of CSF1R/CSF1R, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR150 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0375E2ACP1L)
The PathHunter GPR150 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR150 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR150 and EA-tagged β-Arrestin-2. Activation of GPR150 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Human Adiponectin ASY
The Meso Scale Discovery U-PLEX Human Adiponectin Assay Kit quantifies adiponectin in human serum plasma and cell culture supernatants using electrochemiluminescent detection It features MSD s SULFO-TAG labels and multi-array plate technology for high sensitivity and minimal interference The kit includes a 96-well plate with capture antibodies detection antibodies with ruthenium labels calibrators and necessary reagents The assay takes about 3 5 hours facilitating adiponectin measurement in studies on obesity diabetes and cardiovascular disease
Eurofins Discoverx PathHunter eXpress GPR26 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0392E2ACP1L)
The PathHunter GPR26 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR26 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR26 and EA-tagged β-Arrestin-2. Activation of GPR26 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR37L1 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0378E2ACP1M)
The PathHunter GPR37L1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR37L1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR37L1 and EA-tagged β-Arrestin-2. Activation of GPR37L1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Hach Company SC4500 Ctrl Prog Prof DP 1 mA
SC4500 Controller-Prognosys-Profibus DP-1 mA Input-100-240 VAC-without plug C1D2Includes Controller-Non-Claros Embedded Prognosys-without power cord includes mounting hardware
American Research Products Inc Pig Lysyl OXidase ELISA Kit
Pig Lysyl OXidase ELISA Kit from CUSABIO Detection Range 1 56 ng/mL-100 ng/mL Sensitivity 0 39 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Eurofins Discoverx cAMP Hunter eXpress OPRL1 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0115E2CP2L)
The cAMP Hunter OPRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. orphanin FQ) based activation of OPRL1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type OPRL1, a naturally Gi/Go coupled GPCR. Upon activation of OPRL1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress VIPR1 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0093E2CP2M)
The cAMP Hunter VIPR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. VIP) based activation of VIPR1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type VIPR1, a naturally Gs coupled GPCR. Upon activation of VIPR1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GCGR CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0241E2CP0L)
The PathHunter GCGR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. glucagon) based activation of GCGR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GCGR and EA-tagged β-Arrestin-2. Activation of GCGR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress TrkB-P75 Functional Assay, 10-Plate Kit. (93-0530E3CP16L)
The PathHunter eXpress TrkB-P75 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated TrkB and P75 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged TrkB and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, P75. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.